Coreg and Diprolene drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Coreg (carvedilol) and Diprolene (betamethasone dipropionate). Common drug interactions include dermatitis psoriasiform among females and renal failure among males.
The phase IV clinical study analyzes what interactions people have when they take Coreg and Diprolene. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Coreg?
Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,583 Coreg users. Check the latest studies of Coreg.
What is Diprolene?
Diprolene has active ingredients of betamethasone dipropionate. eHealthMe is studying from 1,048 Diprolene users. Check the latest studies of Diprolene.
15 people who take Coreg and Diprolene together, and have interactions are studied.

What are the common drug interactions of Coreg and Diprolene, by gender? *:
female:
- Dermatitis psoriasiform (large white or silver flakes on the skin)
- Skin infection
- Cellulitis (infection under the skin)
- Chronic kidney disease
- Dizziness
- Renal failure (kidney dysfunction)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Urate nephropathy (disease or abnormality of the kidney)
male:
- Renal failure (kidney dysfunction)
- Chronic kidney disease
- Acute respiratory failure
- Anger
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Apnoea (suspension of external breathing)
- Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
- Asthenia (weakness)
- Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
What are the common drug interactions of Coreg and Diprolene, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Panic attack
- Post procedural complication
- Procedural nausea
- Procedural pain
- Procedural vomiting
- Surgery
- Tension (the act or process of stretching something tight)
- Tension headache
- Anger
- Back pain
40-49:
- Hypoaesthesia (reduced sense of touch or sensation)
- Hypotension (abnormally low blood pressure)
50-59:
- Renal failure (kidney dysfunction)
- Abdominal distension
- Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
- Acute respiratory failure
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Apnoea (suspension of external breathing)
- Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
- Asthenia (weakness)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Balance disorder
60+:
- Dermatitis psoriasiform (large white or silver flakes on the skin)
- Skin infection
- Cellulitis (infection under the skin)
- Chronic kidney disease
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Coagulopathy (blood's ability to clot is impaired)
- Dizziness
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Syncope (loss of consciousness with an inability to maintain postural tone)
What are the existing conditions these people have? *
- Indigestion: 7 people, 46.67%
- Hyperuricaemia (level of uric acid in the blood that is abnormally high): 5 people, 33.33%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 33.33%
- Rash Pustular (redness with pustules): 5 people, 33.33%
- Bladder Transitional Cell Carcinoma (types of bladder cancer): 5 people, 33.33%
- Psoriasis (immune-mediated disease that affects the skin): 5 people, 33.33%
- Pain In Extremity: 5 people, 33.33%
- Cardiac Failure: 5 people, 33.33%
- Itching: 5 people, 33.33%
- Pain: 4 people, 26.67%
* Approximation only. Some reports may have incomplete information.
Do you take Coreg and Diprolene?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Coreg and Diprolene:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Coreg:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Diprolene:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Coreg and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Diprolene and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on carvedilol and betamethasone dipropionate (the active ingredients of Coreg and Diprolene, respectively), and Coreg and Diprolene (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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