Coreg and Golytely drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Coreg (carvedilol) and Golytely (polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride; sodium sulfate, anhydrous). Common drug interactions include abdominal pain among females and gastrointestinal haemorrhage among males.
The phase IV clinical study analyzes what interactions people have when they take Coreg and Golytely. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.
What is Coreg?
Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,583 Coreg users. Check the latest studies of Coreg.
What is Golytely?
Golytely has active ingredients of polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride; sodium sulfate, anhydrous. eHealthMe is studying from 907 Golytely users. Check the latest studies of Golytely.
28 people who take Coreg and Golytely together, and have interactions are studied.

What are the common drug interactions of Coreg and Golytely, by gender? *:
female:
- Abdominal pain
- Gastroenteritis (inflammation of stomach and intestine)
- Headache (pain in head)
- Abdominal distension
- Abdominal pain upper
- Blood glucose increased
- Nausea (feeling of having an urge to vomit)
- Rectal haemorrhage (bleeding from anus)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Pneumonia
male:
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Weight decreased
- Intracardiac thrombus (presence of a circumscribed mass with heart wall)
- Mitral valve incompetence (inefficient heart valve)
- Multiple injuries
- Pulmonary hypertension (increase in blood pressure in the lung artery)
- Surgery
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Tachypnoea (a condition of rapid breathing over 20 per minute)
- Tricuspid valve incompetence (inefficient heart valve)
What are the common drug interactions of Coreg and Golytely, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Gastroenteritis (inflammation of stomach and intestine)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Pneumonia
30-39:
n/a
40-49:
n/a
50-59:
- Weight decreased
- Surgery
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Cardiac failure
- Congestive cardiomyopathy (weakening of heart muscle)
- Ejection fraction decreased (systolic heart failure)
- Hypotension (abnormally low blood pressure)
- Intracardiac thrombus (presence of a circumscribed mass with heart wall)
- Mitral valve incompetence (inefficient heart valve)
60+:
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Headache (pain in head)
- Gingival ulceration (ulcer on gums)
- Infusion site extravasation (flow of (blood or lymph) from infusion site)
- Insomnia (sleeplessness)
- Lumbar hernia (a type of abdominal hernia that affects the lower back)
- Memory impairment
- Periorbital oedema (swelling around the eyes)
- Rectal haemorrhage (bleeding from anus)
- Abdominal pain lower
What are the existing conditions these people have? *
- Hypersensitivity: 8 people, 28.57%
- Diabetes: 6 people, 21.43%
- Pain: 6 people, 21.43%
- Wheezing (a high-pitched whistling sound made while you breath): 5 people, 17.86%
- Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 5 people, 17.86%
- Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 5 people, 17.86%
- Chronic Kidney Disease: 4 people, 14.29%
- Stress And Anxiety: 4 people, 14.29%
- Nausea (feeling of having an urge to vomit): 3 people, 10.71%
- Nausea And Vomiting: 3 people, 10.71%
* Approximation only. Some reports may have incomplete information.
Do you take Coreg and Golytely?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Coreg and Golytely:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Coreg:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Golytely:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Coreg and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Golytely and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on carvedilol and polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride; sodium sulfate, anhydrous (the active ingredients of Coreg and Golytely, respectively), and Coreg and Golytely (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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