Coreg and Methotrexate sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Coreg (carvedilol) and Methotrexate sodium (methotrexate sodium). Common drug interactions include diarrhoea among females and cardiac disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Coreg and Methotrexate sodium. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Coreg?

Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,583 Coreg users. Check the latest studies of Coreg.

What is Methotrexate sodium?

Methotrexate sodium has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. eHealthMe is studying from 97,679 Methotrexate sodium users. Check the latest studies of Methotrexate sodium.

On Jul, 20, 2026

39 people who take Coreg and Methotrexate sodium together, and have interactions are studied.

Coreg and Methotrexate sodium drug interactions.

What are the common drug interactions of Coreg and Methotrexate Sodium, by gender? *:

female:

Diarrhoea
Abdominal pain
Abdominal pain upper
Balance disorder
Contusion (a type of hematoma of tissue in which capillaries)
Drug ineffective
Fall
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Drug hypersensitivity
Pain

male:

Cardiac disorder
Chest pain
Pancreatic disorder
Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)
Post procedural haemorrhage (post procedural bleeding)
Blood creatinine increased
Drug ineffective
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Malignant neoplasm progression (cancer tumour came back)
Peripheral sensory neuropathy (damage to one or more of your peripheral nerves)

What are the common drug interactions of Coreg and Methotrexate Sodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Flushing (the warm, red condition of human skin)
Headache (pain in head)
Irritability
Pain
Peripheral sensory neuropathy (damage to one or more of your peripheral nerves)

60+:

Contusion (a type of hematoma of tissue in which capillaries)
Diarrhoea
Pain
Anaphylactic reaction (serious allergic reaction)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Malaise (a feeling of general discomfort or uneasiness)
Rash
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Anxiety
Gastric disorder (disease of stomach)

What are the existing conditions these people have? *

Chest Pain: 4 people, 10.26%
High Blood Cholesterol: 3 people, 7.69%
Cardiac Disorder: 3 people, 7.69%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 5.13%
Pain: 2 people, 5.13%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 5.13%
Arrhythmias (irregular heartbeat): 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

Do you take Coreg and Methotrexate sodium?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously