Coreg and Nateglinide drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Coreg (carvedilol) and Nateglinide (nateglinide). Common drug interactions include asthma among females and nephrogenic systemic fibrosis among males.
The phase IV clinical study analyzes what interactions people have when they take Coreg and Nateglinide. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.
What is Coreg?
Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,583 Coreg users. Check the latest studies of Coreg.
What is Nateglinide?
Nateglinide has active ingredients of nateglinide. It is often used in type 2 diabetes. eHealthMe is studying from 1,771 Nateglinide users. Check the latest studies of Nateglinide.
26 people who take Coreg and Nateglinide together, and have interactions are studied.

What are the common drug interactions of Coreg and Nateglinide, by gender? *:
female:
- Asthma
- Pneumonia
- Wound infection
- Abdominal pain
- Anxiety
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Bone pain
- Cardiac failure congestive
- Chest pain
- Chronic kidney disease
male:
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
- Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
- Pain
- Quadriparesis (muscle weakness affecting all four limbs)
- Rash pruritic (redness with itching)
- Skin hypertrophy (skin cells enlarges)
- Skin lesion
- Skin tightness
- Abdominal pain upper
- Cardiac failure congestive
What are the common drug interactions of Coreg and Nateglinide, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Cardiovascular disorder (heart diseases)
- Chronic kidney disease
- Depression
- Diabetic vascular disorder (diseases of the blood vessels due to diabetes)
- Erythema (redness of the skin)
- Essential hypertension (primary hypertension)
- Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
- General physical health deterioration (weak health status)
50-59:
- Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
- General physical health deterioration (weak health status)
- Joint contracture (a permanent shortening of a muscle or joint)
- Joint range of motion decreased (disease of joint movement)
- Joint stiffness
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
- Myosclerosis (hardening of muscle tissue)
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
- Oedema (fluid collection in tissue)
- Oedema peripheral (superficial swelling)
60+:
- Asthma
- Pneumonia
- Cardiac failure congestive
- Chest pain
- Dyspnoea (difficult or laboured respiration)
- Ejection fraction decreased (systolic heart failure)
- Fatigue (feeling of tiredness)
- Hyperglycaemia (high blood sugar)
- Oxygen saturation decreased
- Pulmonary mass
What are the existing conditions these people have? *
- Pain: 5 people, 19.23%
- Stress And Anxiety: 3 people, 11.54%
- Nuclear Magnetic Resonance Imaging Brain: 3 people, 11.54%
- Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 3 people, 11.54%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.54%
- Diabetes: 3 people, 11.54%
- Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 11.54%
- Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 2 people, 7.69%
- Neuropathy Peripheral (surface nerve damage): 2 people, 7.69%
- High Blood Cholesterol: 2 people, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Coreg and Nateglinide?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Coreg (49,583 reports)
- Nateglinide (1,771 reports)
Browse all drug interactions of Coreg and Nateglinide:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Coreg:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Nateglinide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Coreg and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nateglinide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on carvedilol and nateglinide (the active ingredients of Coreg and Nateglinide, respectively), and Coreg and Nateglinide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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