Coreg and Septra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Coreg (carvedilol) and Septra (sulfamethoxazole; trimethoprim). Common drug interactions include contusion among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Coreg and Septra. It is created by eHealthMe based on reports of 86 people who take the same drugs from the FDA, and is updated regularly.

What is Coreg?

Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,583 Coreg users. Check the latest studies of Coreg.

What is Septra?

Septra has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 10,280 Septra users. Check the latest studies of Septra.

On Aug, 09, 2026

86 people who take Coreg and Septra together, and have interactions are studied.

What are the common drug interactions of Coreg and Septra, by gender? *:

female:

Contusion (a type of hematoma of tissue in which capillaries)
Anaemia (lack of blood)
Dyspnoea (difficult or laboured respiration)
Abdominal pain
Fall
Cellulitis (infection under the skin)
Dehydration (dryness resulting from the removal of water)
Fatigue (feeling of tiredness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood urea increased

male:

Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)
Diarrhoea
Weight decreased
Abdominal pain upper
Anxiety
Arthralgia (joint pain)
Death
Dizziness
International normalised ratio increased

What are the common drug interactions of Coreg and Septra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Graft dysfunction
Hyperkalaemia (damage to or disease of the kidney)
Transplant rejection (a transplant material is not worked)
Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Diarrhoea

20-29:

Drug hypersensitivity
Pneumonia
Pulmonary toxicity (side effects on the lungs)
Respiratory failure (inadequate gas exchange by the respiratory system)
Thrombocytopenia (decrease of platelets in blood)
Hypotension (abnormally low blood pressure)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Pulmonary oedema (fluid accumulation in the lungs)

30-39:

Abdominal pain upper
Alcohol use
Arrhythmia (irregular heartbeat)
Blood thyroid stimulating hormone increased
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Contusion (a type of hematoma of tissue in which capillaries)
Cytomegalovirus test positive
Electrocardiogram qt corrected interval prolonged
Electrocardiogram qt prolonged

40-49:

Injury
Kidney transplant rejection
Pain
Arthralgia (joint pain)
Complications of transplanted kidney
Dyspnoea (difficult or laboured respiration)
Guillain-barre syndrome (the body's immune system attacks its peripheral nervous system)
Hypotension (abnormally low blood pressure)
Muscular weakness (muscle weakness)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

50-59:

Diarrhoea
Renal failure (kidney dysfunction)
Loss of consciousness
Myocarditis (inflammation of heart muscle myocardium)
Pulse absent
Abdominal distension
Abdominal pain upper
Abscess (pus)
Anaemia (lack of blood)
Arthralgia (joint pain)

60+:

Nausea (feeling of having an urge to vomit)
Vomiting
Fall
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Decreased appetite
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Renal failure (kidney dysfunction)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Weight decreased

What are the existing conditions these people have? *

High Blood Cholesterol: 7 people, 8.14%
Cardiac Disorder: 7 people, 8.14%
Multiple Myeloma (cancer of the plasma cells): 6 people, 6.98%
Transplant Rejection (a transplant material is not worked): 5 people, 5.81%
Swelling: 5 people, 5.81%
Pain: 5 people, 5.81%
Infection: 5 people, 5.81%
Gout (uric acid crystals building up in the body): 5 people, 5.81%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 5.81%
Dyspnea (difficult or laboured breathing): 5 people, 5.81%

* Approximation only. Some reports may have incomplete information.

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