Corgard and Ultram drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Corgard (nadolol) and Ultram (tramadol hydrochloride). Common drug interactions include acute coronary syndrome among females and ascites among males.

The phase IV clinical study analyzes what interactions people have when they take Corgard and Ultram. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Corgard?

Corgard has active ingredients of nadolol. It is often used in high blood pressure. eHealthMe is studying from 3,342 Corgard users. Check the latest studies of Corgard.

What is Ultram?

Ultram has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 28,425 Ultram users. Check the latest studies of Ultram.

On Aug, 08, 2026

43 people who take Corgard and Ultram together, and have interactions are studied.

What are the common drug interactions of Corgard and Ultram, by gender? *:

female:

Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Agitation (state of anxiety or nervous excitement)
Alanine aminotransferase increased
Alopecia (absence of hair from areas of the body)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Aortic valve incompetence
Aphasia (damage to the parts of the brain that control language)
Application site discharge
Arrhythmia (irregular heartbeat)
Arterial stent insertion

male:

Ascites (accumulation of fluid in the abdominal cavity)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Liver disorder (liver diseases)
Mitral valve incompetence (inefficient heart valve)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Oedema lower limb (fluid collection in tissue of lower leg)
Oedema peripheral (superficial swelling)
Panniculitis (inflammation of the subcutaneous fat)

What are the common drug interactions of Corgard and Ultram, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abortion induced (medically referred abortion)
Anxiety
Blindness
Deafness
Depression
Disturbance in attention
Facial pain
Headache (pain in head)
Injury
Intracranial venous sinus thrombosis (presence of thrombosis (a blood clot) in the dural venous sinuses, which drain blood from the brain)

30-39:

Flushing (the warm, red condition of human skin)
Sweating increased (excess sweating)
Vomiting

40-49:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetes mellitus inadequate control
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Hyperglycaemic hyperosmolar nonketotic syndrome (too much sugar (glucose) in your blood)
Insulin-requiring type 2 diabetes mellitus
Type 1 diabetes mellitus
Type 2 diabetes mellitus
Psoriasis (immune-mediated disease that affects the skin)

50-59:

Anxiety
Aphasia (damage to the parts of the brain that control language)
Arrhythmia (irregular heartbeat)
Arterial stent insertion
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Aspartate aminotransferase increased
Asthma
Atelectasis (partial or complete collapse of the lung)

60+:

Deafness
Dyspnoea (difficult or laboured respiration)
Oedema peripheral (superficial swelling)
Orthopnoea (shortness of breath (dyspnea) when lying down)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Sweating increased (excess sweating)
Urinary tract infection
Valvular heart disease (diseases of the heart valves)

What are the existing conditions these people have? *

Depression: 7 people, 16.28%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 13.95%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 4 people, 9.30%
Nausea (feeling of having an urge to vomit): 4 people, 9.30%
Itching: 4 people, 9.30%
Cardiac Disorder: 4 people, 9.30%
Migraine (headache): 3 people, 6.98%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 6.98%

* Approximation only. Some reports may have incomplete information.

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