Cosentyx and Estradiol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cosentyx (secukinumab) and Estradiol (estradiol). Common drug interactions include drug ineffective among females.

The phase IV clinical study analyzes what interactions people have when they take Cosentyx and Estradiol. It is created by eHealthMe based on reports of 87 people who take the same drugs from the FDA, and is updated regularly.

What is Cosentyx?

Cosentyx has active ingredients of secukinumab. It is often used in psoriatic arthritis. eHealthMe is studying from 187,247 Cosentyx users. Check the latest studies of Cosentyx.

What is Estradiol?

Estradiol has active ingredients of estradiol. It is often used in menopause. eHealthMe is studying from 18,986 Estradiol users. Check the latest studies of Estradiol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

87 people who take Cosentyx and Estradiol together, and have interactions are studied.

Cosentyx and Estradiol drug interactions.

What are the common drug interactions of Cosentyx and Estradiol, by gender? *:

female:

Drug ineffective
Pain
Polyp
Retroperitoneal lymphadenopathy (disease of lymph node between peritoneum and the posterior abdominal wall)
Tumour invasion (starting of tumour)
Arthralgia (joint pain)
Alopecia (absence of hair from areas of the body)
Mobility decreased (ability to move is reduced)
Back pain
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)

male:

n/a

What are the common drug interactions of Cosentyx and Estradiol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal discomfort
Alopecia (absence of hair from areas of the body)
Cough
Dactylitis (dactylitis or sausage digit is inflammation of an entire digit (a finger or toe), and can be painful)
Dyspnoea (difficult or laboured respiration)
Enthesopathy (disorder of entheses (bone attachments))
Psoriasis (immune-mediated disease that affects the skin)
Rash
Rectal haemorrhage (bleeding from anus)
Spinal osteoarthritis (joint cartilage loss in spine)

40-49:

Asthma
Pain
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Discomfort
Rash
Drug ineffective
Injection site pain
Malaise (a feeling of general discomfort or uneasiness)
Vision blurred
Visual impairment

50-59:

Hepatotoxicity (chemical-driven liver damage)
Hyperhidrosis (abnormally increased sweating)
Hypertension (high blood pressure)
Insomnia (sleeplessness)
Joint swelling
Malaise (a feeling of general discomfort or uneasiness)
Pneumonia
Pyrexia (fever)
Retinal artery occlusion (blockage of retinal artery)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

60+:

Vomiting
Drug ineffective
Colitis microscopic (inflammation of colon with diarrhoea and abdominal cramps)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Drug hypersensitivity
Glaucoma (increased fluid pressure in the eye with vision loss)
Hepatic enzyme increased
Hypertension (high blood pressure)
Insomnia (sleeplessness)
Intestinal polyp (small growths in the bowel with the potential for further growth)

What are the existing conditions these people have? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 46 people, 52.87%
Psoriasis (immune-mediated disease that affects the skin): 22 people, 25.29%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 19 people, 21.84%
Nausea (feeling of having an urge to vomit): 7 people, 8.05%
High Blood Pressure: 7 people, 8.05%
Ankylosing Spondylitis (type of arthritis affecting the spine): 7 people, 8.05%
Pain: 6 people, 6.90%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 5 people, 5.75%

* Approximation only. Some reports may have incomplete information.

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