Cotrim and Nulytely drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cotrim (sulfamethoxazole; trimethoprim) and Nulytely (polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride). Common drug interactions include bradyphrenia among females and abscess intestinal among males.

The phase IV clinical study analyzes what interactions people have when they take Cotrim and Nulytely. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Cotrim?

Cotrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 8,890 Cotrim users. Check the latest studies of Cotrim.

What is Nulytely?

Nulytely has active ingredients of polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride. eHealthMe is studying from 1,377 Nulytely users. Check the latest studies of Nulytely.

On Jul, 17, 2026

18 people who take Cotrim and Nulytely together, and have interactions are studied.

What are the common drug interactions of Cotrim and Nulytely, by gender? *:

female:

Bradyphrenia (neurological term referring to the slowness of thought common to many disorders of the brain)
Pyrexia (fever)
Somnolence (a state of near-sleep, a strong desire for sleep)
Staphylococcal infection (an infection with staphylococcus bacteria)
Disturbance in social behaviour
Febrile neutropenia (fever with reduced white blood cells)
Haemorrhage (bleeding)
Infection
Libido increased (increased sexual urge to have sex)
Rash

male:

Abscess intestinal (collections of pus-intestinal)
Asthenia (weakness)
Pulmonary embolism (blockage of the main artery of the lung)
Respiratory failure (inadequate gas exchange by the respiratory system)
Skin necrosis (skin damage)
White blood cell count decreased
Chest pain
Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
Febrile neutropenia (fever with reduced white blood cells)
Mediastinitis (inflammation of the tissues in the mid-chest)

What are the common drug interactions of Cotrim and Nulytely, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Febrile neutropenia (fever with reduced white blood cells)
Haemorrhage (bleeding)
Infection
Anal haemorrhage
Epistaxis (bleed from the nose)

20-29:

n/a

30-39:

n/a

40-49:

Bradyphrenia (neurological term referring to the slowness of thought common to many disorders of the brain)
Somnolence (a state of near-sleep, a strong desire for sleep)
Pyrexia (fever)
Staphylococcal infection (an infection with staphylococcus bacteria)
Urinary tract infection
Drug hypersensitivity
Haemoglobin decreased
Haemostasis (stopping of bleeding)
Hepatitis (inflammation of the liver)
Overdose

50-59:

Disturbance in social behaviour
Libido increased (increased sexual urge to have sex)
Agitation (state of anxiety or nervous excitement)
Confusional state
Dyskinesia (abnormality or impairment of voluntary movement)
Dystonia (abnormal muscle tone)
Hallucination, visual (seeing things that aren't there)
Hospitalisation
Muscle spasms (muscle contraction)
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)

60+:

Abdominal pain
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Pruritus (severe itching of the skin)
Pulmonary embolism (blockage of the main artery of the lung)
Pyrexia (fever)
Rash
Respiratory failure (inadequate gas exchange by the respiratory system)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Vomiting
White blood cell count decreased

What are the existing conditions these people have? *

Pain: 7 people, 38.89%
Constipation: 4 people, 22.22%
Ovarian Cancer (cancer of ovary): 4 people, 22.22%
Nausea And Vomiting: 4 people, 22.22%
Depression: 3 people, 16.67%
Gastritis (inflammation of stomach): 3 people, 16.67%
High Blood Pressure: 2 people, 11.11%
Haemostasis (stopping of bleeding): 2 people, 11.11%
Agitation (state of anxiety or nervous excitement): 2 people, 11.11%
Device Related Infection: 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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