Coumadin and Sirolimus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Coumadin (warfarin sodium) and Sirolimus (sirolimus). Common drug interactions include dysphonia among females and diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Coumadin and Sirolimus. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Coumadin?

Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. eHealthMe is studying from 133,228 Coumadin users. Check the latest studies of Coumadin.

What is Sirolimus?

Sirolimus has active ingredients of sirolimus. eHealthMe is studying from 11,823 Sirolimus users. Check the latest studies of Sirolimus.

On Jul, 12, 2026

36 people who take Coumadin and Sirolimus together, and have interactions are studied.

Coumadin and Sirolimus drug interactions.

What are the common drug interactions of Coumadin and Sirolimus, by gender? *:

female:

Dysphonia (speech disorder attributable to a disorder of phonation)
Malaise (a feeling of general discomfort or uneasiness)
Pulmonary mycosis (lung infection caused by yeast-like fungi)
Secretion discharge
Dehydration (dryness resulting from the removal of water)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Abdominal pain
Anaemia (lack of blood)
Empyema (collection of pus in a cavity in the body)
Fistula (an abnormal connection or passageway between two)

male:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Aphthous stomatitis (mouth ulcer)
Arteriosclerosis (thickening and hardening of arteries)
Asthma
Back pain
Blood creatine phosphokinase increased
Blood creatine phosphokinase mb increased
Blood glucose fluctuation

What are the common drug interactions of Coumadin and Sirolimus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

40-49:

Gastroenteritis (inflammation of stomach and intestine)
Dehydration (dryness resulting from the removal of water)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

50-59:

Pancreatic disorder
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonia viral
Prostate cancer
Prostatomegaly (enlargement of the prostate)
Proteinuria (presence of protein in the urine)
Renal cyst (kidney cyst)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Serum ferritin increased
Sinusitis (inflammation of sinus)

60+:

Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Renal failure acute (rapid kidney dysfunction)
Secretion discharge
Enterococcal infection
Faeces discoloured
Medical device complication
Psychiatric symptom
Vomiting
Pulmonary oedema (fluid accumulation in the lungs)
Asthenia (weakness)

What are the existing conditions these people have? *

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 8 people, 22.22%
Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 8 people, 22.22%
Antiphospholipid Syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss): 3 people, 8.33%
High Blood Pressure: 2 people, 5.56%
Diabetes: 2 people, 5.56%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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