Coreg and Tyvaso drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Coreg (carvedilol) and Tyvaso (treprostinil sodium). Common drug interactions include oxygen saturation decreased among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Coreg and Tyvaso. It is created by eHealthMe based on reports of 75 people who take the same drugs from the FDA, and is updated regularly.
What is Coreg?
Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,583 Coreg users. Check the latest studies of Coreg.
What is Tyvaso?
Tyvaso has active ingredients of treprostinil sodium. eHealthMe is studying from 37,941 Tyvaso users. Check the latest studies of Tyvaso.
75 people who take Coreg and Tyvaso together, and have interactions are studied.

What are the common drug interactions of Coreg and Tyvaso, by gender? *:
female:
- Oxygen saturation decreased
- Dizziness
- Haemoglobin decreased
- Nausea (feeling of having an urge to vomit)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Cardiac arrest
- Death
- Heart rate irregular
- Pulmonary oedema (fluid accumulation in the lungs)
- Sinusitis (inflammation of sinus)
male:
- Dyspnoea (difficult or laboured respiration)
- Cough
- Cardiac failure
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Chronic respiratory failure
- Confusional state
- Hypercapnia (too much smoke)
- Hypoxia (low oxygen in tissues)
- Nausea (feeling of having an urge to vomit)
- Oxygen saturation decreased
What are the common drug interactions of Coreg and Tyvaso, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Sinusitis (inflammation of sinus)
40-49:
- Dyspnoea (difficult or laboured respiration)
- Headache (pain in head)
- Cough
- Pain in extremity
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Cellulitis (infection under the skin)
- Contusion (a type of hematoma of tissue in which capillaries)
- Decreased appetite
- Exercise tolerance decreased
- Fatigue (feeling of tiredness)
50-59:
- Blood urine present
- Decreased appetite
- Diarrhoea
- Dysgeusia (disorder of the sense of taste)
- Dyspepsia (indigestion)
- Fatigue (feeling of tiredness)
- Glossodynia (a burning or painful sensation in the tongue)
- Haematocrit decreased
- Insomnia (sleeplessness)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
60+:
- Headache (pain in head)
- Dyspnoea (difficult or laboured respiration)
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Eye pain
- Insomnia (sleeplessness)
- Jugular vein distension (overloaded jugular vein)
- Nasal discomfort
- Oropharyngeal discomfort (pain or irritation of oropharynx)
- Oropharyngeal pain
- Respiratory disorder (respiratory disease)
What are the existing conditions these people have? *
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 55 people, 73.33%
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 15 people, 20.00%
- Pain: 4 people, 5.33%
* Approximation only. Some reports may have incomplete information.
Do you take Coreg and Tyvaso?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Coreg and Tyvaso:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Coreg:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tyvaso:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Coreg and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tyvaso and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on carvedilol and treprostinil sodium (the active ingredients of Coreg and Tyvaso, respectively), and Coreg and Tyvaso (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Tymlos cause Drowsiness? - now
- Could Adderall 5 cause Actinic Keratosis? - 9 seconds ago
- Drug interactions of Lanoxin and Nolvadex - 19 seconds ago
- Could Ventolin cause Paranoia? - 28 seconds ago
- Could Lanreotide Acetate cause Muscle Spasms? - 34 seconds ago
- Drug interactions of Combivent Respimat and Novolog - 45 seconds ago
- Could Venlafaxine Hydrochloride cause Bone Pain Aggravated? - 48 seconds ago
- Drug interactions of Ranitidine Hydrochloride and Tykerb - 51 seconds ago
- Could Nicotrol cause Pneumonia? - 54 seconds ago
- Could Prozac cause Salivary Hypersecretion? - a minute ago