Ranitidine hydrochloride and Tykerb drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ranitidine hydrochloride (ranitidine hydrochloride) and Tykerb (lapatinib ditosylate). Common drug interactions include palmar-plantar erythrodysaesthesia syndrome among females.

The phase IV clinical study analyzes what interactions people have when they take Ranitidine hydrochloride and Tykerb. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Ranitidine hydrochloride?

Ranitidine hydrochloride has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 76,413 Ranitidine hydrochloride users. Check the latest studies of Ranitidine hydrochloride.

What is Tykerb?

Tykerb has active ingredients of lapatinib ditosylate. It is often used in breast cancer. eHealthMe is studying from 12,231 Tykerb users. Check the latest studies of Tykerb.

On Jul, 12, 2026

14 people who take Ranitidine hydrochloride and Tykerb together, and have interactions are studied.

Ranitidine hydrochloride and Tykerb drug interactions.

What are the common drug interactions of Ranitidine Hydrochloride and Tykerb, by gender? *:

female:

Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Anaemia (lack of blood)
Cholangitis (infection of the bile duct)
Liver abscess (pus in liver)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hepatic failure (liver failure)
Mouth haemorrhage (bleeding from mouth)
Disease progression
Ejection fraction decreased (systolic heart failure)
General physical health deterioration (weak health status)

male:

n/a

What are the common drug interactions of Ranitidine Hydrochloride and Tykerb, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Ejection fraction decreased (systolic heart failure)
General physical health deterioration (weak health status)

50-59:

Decreased appetite
Fatigue (feeling of tiredness)
Cholangitis (infection of the bile duct)
Liver abscess (pus in liver)
Blood calcium decreased
Blood chloride decreased
Blood potassium decreased
Blood sodium decreased
Haematocrit decreased
Haemoglobin decreased

60+:

Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Anaemia (lack of blood)
Mouth haemorrhage (bleeding from mouth)
Disease progression
Drug intolerance (drug sensitivity)
Malignant neoplasm progression (cancer tumour came back)
Thrombocytopenia (decrease of platelets in blood)
Diarrhoea
Drug ineffective
Febrile neutropenia (fever with reduced white blood cells)

What are the existing conditions these people have? *

Rashes (redness): 6 people, 42.86%
Swallowing Difficulty: 3 people, 21.43%
Nausea (feeling of having an urge to vomit): 3 people, 21.43%
Metastases To Skin (cancer spreads to skin): 3 people, 21.43%
Febrile Neutropenia (fever with reduced white blood cells): 3 people, 21.43%
Dizziness: 3 people, 21.43%
Diarrhea: 3 people, 21.43%
Conjunctivitis (pink eye): 3 people, 21.43%
Abdominal Pain: 3 people, 21.43%
General Physical Health Deterioration (weak health status): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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