Semglee and Headache - a phase IV clinical study of FDA data

Summary:

Headache is reported as a side effect among people who take Semglee (insulin glargine), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Metformin, and have Diabetes.

The phase IV clinical study analyzes which people have Headache when taking Semglee. It is created by eHealthMe based on reports of 1,737 people who have side effects when taking Semglee from the FDA, and is updated regularly.

What is Semglee?

Semglee has active ingredients of insulin glargine. eHealthMe is studying from 1,750 Semglee users. Check the latest studies of Semglee.

What is Headache?

Headache (pain in head) is found to be associated with 3,753 drugs and 5,772 conditions by eHealthMe. Check the latest studies of Headache.

On Jul, 12, 2026

1,737 people reported to have side effects when taking Semglee.
Among them, 16 people (0.92%) have Headache.

Among these 16 people:

How long have people been on Semglee when they have Headache? *

What is the gender of people who have Headache when taking Semglee? *

female: 64.29 %
male: 35.71 %

What is the age of people who have Headache when taking Semglee? *

What are other drugs people take besides Semglee? *

What are other side effects people have besides Headache? *

Vision Blurred: 5 people, 31.25%
Nausea (feeling of having an urge to vomit): 4 people, 25.00%
High Blood Pressure: 4 people, 25.00%
Drug Hypersensitivity: 2 people, 12.50%
Dizziness: 2 people, 12.50%
Balance Disorder: 2 people, 12.50%
Skin Blushing/flushing (a sudden reddening of the face, neck): 2 people, 12.50%
Diarrhea: 2 people, 12.50%
Visual Impairment: 1 person, 6.25%
Chest Pain: 1 person, 6.25%

What are the existing conditions these people have? *

Diabetes: 5 people, 31.25%
Type 1 Diabetes: 3 people, 18.75%
Type 2 Diabetes: 2 people, 12.50%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 6.25%
Myxoedema (a disease caused by decreased activity of the thyroid gland in adults and characterized by dry skin, swellings): 1 person, 6.25%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 6.25%
Indigestion: 1 person, 6.25%
Iga Nephropathy (kidney disease- condition prevents the kidneys from filtering waste): 1 person, 6.25%
Heart Attack: 1 person, 6.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Semglee and have Headache?

- Check whether Headache is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Semglee:

Semglee (1,750 reports)

Headache treatments and more:

Headache (756,642 reports)

Browse all side effects of Semglee:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Headache:

Headache (3,753 drugs)

Browse all the conditions that are associated with Headache:

Headache (5,772 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on insulin glargine (the active ingredients of Semglee) and Semglee (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.