Cozaar and Suboxone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cozaar (losartan potassium) and Suboxone (buprenorphine hydrochloride; naloxone hydrochloride). Common drug interactions include pain among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Cozaar and Suboxone. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Cozaar?

Cozaar has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 45,124 Cozaar users. Check the latest studies of Cozaar.

What is Suboxone?

Suboxone has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. It is often used in opiate withdrawal. eHealthMe is studying from 31,249 Suboxone users. Check the latest studies of Suboxone.

On Jul, 28, 2026

11 people who take Cozaar and Suboxone together, and have interactions are studied.

What are the common drug interactions of Cozaar and Suboxone, by gender? *:

female:

Pain
Vomiting
Abnormal behaviour
Agitation (state of anxiety or nervous excitement)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Bone loss
Chest pain
Confusional state

male:

Headache (pain in head)
Drug dependence
Abdominal pain
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dyspnoea (difficult or laboured respiration)
Heat stroke
Oedema mouth (swelling of mouth)
Panic attack
Therapeutic response decreased (less preventive response)

What are the common drug interactions of Cozaar and Suboxone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Vomiting
Abnormal behaviour
Agitation (state of anxiety or nervous excitement)
Chest pain
Confusional state
Diabetic complication
Diarrhoea
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Fluid retention (an abnormal accumulation of fluid in the blood)
Insomnia (sleeplessness)

30-39:

Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Drug dependence
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Headache (pain in head)
Heat stroke
Oedema mouth (swelling of mouth)
Panic attack
Tobacco user
Toothache (tooth pain)
Vomiting

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Bone loss
Emotional distress
Multiple fractures
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteoporosis (bones weak and more likely to break)
Pain
Pancreatitis (inflammation of pancreas)

50-59:

Nausea (feeling of having an urge to vomit)

60+:

Chest pain
Cough
Dyspnoea (difficult or laboured respiration)
Therapeutic response decreased (less preventive response)
Wheezing (a high-pitched whistling sound made while you breath)
Flushing (the warm, red condition of human skin)
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Headache (pain in head)
Hospitalisation
Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)

What are the existing conditions these people have? *

Drug Dependence: 3 people, 27.27%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 18.18%
Hepatitis C: 2 people, 18.18%
Stress And Anxiety: 1 person, 9.09%
Osteoporosis (bones weak and more likely to break): 1 person, 9.09%
Insomnia (sleeplessness): 1 person, 9.09%
Hiv Infection: 1 person, 9.09%
Diabetes: 1 person, 9.09%
Depression: 1 person, 9.09%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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