Cozaar and Tobramycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cozaar (losartan potassium) and Tobramycin (tobramycin). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Cozaar and Tobramycin. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Cozaar?

Cozaar has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 45,124 Cozaar users. Check the latest studies of Cozaar.

What is Tobramycin?

Tobramycin has active ingredients of tobramycin. It is often used in cystic fibrosis. eHealthMe is studying from 3,579 Tobramycin users. Check the latest studies of Tobramycin.



On Jul, 14, 2026

15 people who take Cozaar and Tobramycin together, and have interactions are studied.

Cozaar and Tobramycin drug interactions.

What are the common drug interactions of Cozaar and Tobramycin, by gender? *:

female:

  1. Chronic kidney disease
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Nephrogenic anaemia (anaemia due to kidney disease)
  4. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  5. Renal failure (kidney dysfunction)

male:

  1. Chronic kidney disease
  2. Pain
  3. Hypotension (abnormally low blood pressure)
  4. Mass
  5. Nephrogenic anaemia (anaemia due to kidney disease)
  6. Prostate cancer
  7. Emotional distress
  8. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  9. Decreased appetite
  10. Discomfort

What are the common drug interactions of Cozaar and Tobramycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Chronic kidney disease
  2. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  3. Nephrogenic anaemia (anaemia due to kidney disease)
  4. Renal failure (kidney dysfunction)
  5. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  6. Renal injury (kidney injury)
  7. Renal tubular necrosis (death of kidney tubules)
  8. Weight decreased

40-49:

  1. Respiratory syncytial virus infection (viral disease of respiratory system)

50-59:

  1. Hypercholesterolaemia (high levels of cholesterol in the blood)
  2. Multiple fractures
  3. Osteonecrosis (death of bone)
  4. Osteopenia (a condition where bone mineral density is lower than normal)
  5. Pain
  6. Renal failure (kidney dysfunction)
  7. Renal impairment (severely reduced kidney function)
  8. Renal injury (kidney injury)
  9. Tooth loss
  10. Chronic kidney disease

60+:

  1. Chronic kidney disease
  2. Depression
  3. Renal failure (kidney dysfunction)
  4. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  5. Decreased appetite
  6. Discomfort
  7. Fatigue (feeling of tiredness)
  8. Infection
  9. Muscle spasms (muscle contraction)
  10. Nasopharyngitis (inflammation of the nasopharynx)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 66.67%
  2. High Blood Cholesterol: 5 people, 33.33%
  3. Infection: 5 people, 33.33%
  4. Diabetes: 5 people, 33.33%
  5. Blood Pressure Abnormal: 4 people, 26.67%
  6. Pain: 4 people, 26.67%
  7. Dyspnea (difficult or laboured breathing): 3 people, 20.00%
  8. Hypersensitivity: 3 people, 20.00%
  9. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 3 people, 20.00%
  10. Thrombosis (formation of a blood clot inside a blood vessel): 3 people, 20.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cozaar and Tobramycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cozaar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tobramycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cozaar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tobramycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on losartan potassium and tobramycin (the active ingredients of Cozaar and Tobramycin, respectively), and Cozaar and Tobramycin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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