Cranberry extract and Synthroid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cranberry extract (cranberry) and Synthroid (levothyroxine sodium). Common drug interactions include drug ineffective among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Cranberry extract and Synthroid. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Cranberry extract?

Cranberry extract has active ingredients of cranberry. It is often used in urinary tract infection. eHealthMe is studying from 512 Cranberry extract users. Check the latest studies of Cranberry extract.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,202 Synthroid users. Check the latest studies of Synthroid.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

39 people who take Cranberry extract and Synthroid together, and have interactions are studied.

Cranberry extract and Synthroid drug interactions.

What are the common drug interactions of Cranberry Extract and Synthroid, by gender? *:

female:

Drug ineffective
Fatigue (feeling of tiredness)
Citrobacter infection (infection by citrobacter (bacteria))
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Hydronephrosis (water inside the kidney)
Nephrolithiasis (calculi in the kidneys)
Pyelocaliectasis
Blood thyroid stimulating hormone increased
Constipation
Headache (pain in head)

male:

Drug ineffective
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Tumour pain
Balance disorder
Constipation
Death
Dyspnoea (difficult or laboured respiration)
Faeces discoloured
Haematoma (collection of blood outside the blood vessels)
Head injury

What are the common drug interactions of Cranberry Extract and Synthroid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Asthenia (weakness)
Drug ineffective
Headache (pain in head)
Pain

40-49:

Citrobacter infection (infection by citrobacter (bacteria))
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Hydronephrosis (water inside the kidney)
Nephrolithiasis (calculi in the kidneys)
Pyelocaliectasis
Nephropathy (damage to or disease of a kidney)
Sepsis (a severe blood infection that can lead to organ failure and death)
Visual impairment
Visual acuity reduced (reduced clearness of vision)
Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)

50-59:

Basal ganglia stroke (basal ganglia stroke occurs is when the flow of blood is blocked from the middle of the brain)
Emotional disorder
Headache (pain in head)
Hypertension (high blood pressure)
Memory impairment
Pain

60+:

Drug ineffective
Constipation
Arthralgia (joint pain)
Asthenia (weakness)
Asthma
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bladder neoplasm (bladder tumour)
Blood creatinine increased
Blood glucose decreased
Blood glucose fluctuation

What are the existing conditions these people have? *

Asthma: 6 people, 15.38%
Muscle Spasms (muscle contraction): 4 people, 10.26%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 10.26%
Depression: 4 people, 10.26%
Pain: 3 people, 7.69%
Nausea (feeling of having an urge to vomit): 3 people, 7.69%
High Blood Pressure: 3 people, 7.69%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 7.69%
Constipation: 2 people, 5.13%
Cardiac Disorder: 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

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