Creon and Clexane drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Creon (pancrelipase (amylase;lipase;protease)) and Clexane (enoxaparin sodium). Common drug interactions include hypotension among females and myoclonus among males.

The phase IV clinical study analyzes what interactions people have when they take Creon and Clexane. It is created by eHealthMe based on reports of 75 people who take the same drugs from the FDA, and is updated regularly.

What is Creon?

Creon has active ingredients of pancrelipase (amylase;lipase;protease). It is often used in pancreatitis. eHealthMe is studying from 29,489 Creon users. Check the latest studies of Creon.

What is Clexane?

Clexane has active ingredients of enoxaparin sodium. eHealthMe is studying from 14,679 Clexane users. Check the latest studies of Clexane.

On Jul, 09, 2026

75 people who take Creon and Clexane together, and have interactions are studied.

What are the common drug interactions of Creon and Clexane, by gender? *:

female:

Hypotension (abnormally low blood pressure)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Infusion related reaction
Ischaemic hepatitis (decreased blood supply to the liver resulting in injury to liver cells)
Lung disorder (lung disease)
Muscular weakness (muscle weakness)
Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)
Pyrexia (fever)
Renal failure acute (rapid kidney dysfunction)
Small intestinal obstruction (blockage in small intestine)

male:

Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
Thrombocytosis
Dehydration (dryness resulting from the removal of water)
Hypercapnia (too much smoke)
Hypoxia (low oxygen in tissues)
Neutropenia (an abnormally low number of neutrophils)
Oedema peripheral (superficial swelling)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Respiratory failure (inadequate gas exchange by the respiratory system)
Vomiting

What are the common drug interactions of Creon and Clexane, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
Mastoiditis (infection of mastoid bone)
Diarrhoea
Nausea (feeling of having an urge to vomit)
Obstruction gastric (obstruction in stomach)
Vomiting

40-49:

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)

50-59:

Hyperglycaemia (high blood sugar)
Hypertensive crisis
Thrombocytosis
Constipation
Flatulence (flatus expelled through the anus)
Anaemia (lack of blood)
Cardiac failure
Diarrhoea
Hypercapnia (too much smoke)
Hypoxia (low oxygen in tissues)

60+:

Bile duct stenosis (abnormal narrowing of the common bile duct)
Sepsis (a severe blood infection that can lead to organ failure and death)
Muscle atrophy (a decrease in the mass of the muscle)
Pyrexia (fever)
Ascites (accumulation of fluid in the abdominal cavity)
International normalised ratio increased
Portal vein thrombosis (venous thrombosis affecting the hepatic portal vein)
Upper respiratory tract infection
Cholangitis (infection of the bile duct)
Death

What are the existing conditions these people have? *

Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 18 people, 24.00%
Adenocarcinoma Pancreas (cancer of pancreas): 18 people, 24.00%
Pancreatic Carcinoma (pancreatic cancer): 17 people, 22.67%
Diabetes: 16 people, 21.33%
High Blood Pressure: 15 people, 20.00%
Pain: 9 people, 12.00%
Depression: 7 people, 9.33%
Respiratory Tract Infection: 6 people, 8.00%
Nausea (feeling of having an urge to vomit): 6 people, 8.00%
Sedation: 5 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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