Creon and Fentanyl citrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Creon (pancrelipase (amylase;lipase;protease)) and Fentanyl citrate (fentanyl citrate). Common drug interactions include bronchitis among females and cholestasis among males.

The phase IV clinical study analyzes what interactions people have when they take Creon and Fentanyl citrate. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Creon?

Creon has active ingredients of pancrelipase (amylase;lipase;protease). It is often used in pancreatitis. eHealthMe is studying from 29,489 Creon users. Check the latest studies of Creon.

What is Fentanyl citrate?

Fentanyl citrate has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 21,294 Fentanyl citrate users. Check the latest studies of Fentanyl citrate.



On Jul, 09, 2026

11 people who take Creon and Fentanyl citrate together, and have interactions are studied.

Creon and Fentanyl citrate drug interactions.

What are the common drug interactions of Creon and Fentanyl Citrate, by gender? *:

female:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Carbon dioxide decreased
  3. Eosinophil count increased
  4. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  5. Mean cell haemoglobin increased (more than normal haemoglobin per red blood cell in a sample of blood)
  6. Pancreatic insufficiency
  7. Productive cough
  8. Pulmonary function test decreased
  9. Respiratory tract infection fungal
  10. Specific gravity urine decreased

male:

  1. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  2. Hepatitis (inflammation of the liver)
  3. Post procedural haematoma (post procedural clotting of blood)

What are the common drug interactions of Creon and Fentanyl Citrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Carbon dioxide decreased
  2. Dyspnoea (difficult or laboured respiration)
  3. Eosinophil count increased
  4. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  5. Mean cell haemoglobin increased (more than normal haemoglobin per red blood cell in a sample of blood)
  6. Pancreatic insufficiency
  7. Productive cough
  8. Pulmonary function test decreased
  9. Respiratory tract infection fungal
  10. Specific gravity urine decreased

10-19:

n/a

20-29:

n/a

30-39:

  1. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  2. Hepatitis (inflammation of the liver)
  3. Post procedural haematoma (post procedural clotting of blood)

40-49:

n/a

50-59:

n/a

60+:

  1. Hyperglycaemia (high blood sugar)
  2. Pyrexia (fever)

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 3 people, 27.27%
  2. Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 27.27%
  3. Syphilis (sexually transmitted , chronic bacterial disease caused by the spirochete treponema pallidum): 2 people, 18.18%
  4. Cholangiocarcinoma (a cancer that forms glands or secretes significant amounts of mucins): 2 people, 18.18%
  5. Anaemia (lack of blood): 2 people, 18.18%
  6. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 18.18%
  7. Nausea And Vomiting: 2 people, 18.18%
  8. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 18.18%
  9. Gastritis (inflammation of stomach): 2 people, 18.18%
  10. Cystic Fibrosis Lung (fibrosis with cyst in the lung): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Creon and Fentanyl citrate?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Creon and Fentanyl citrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Creon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Fentanyl citrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Creon and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fentanyl citrate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on pancrelipase (amylase;lipase;protease) and fentanyl citrate (the active ingredients of Creon and Fentanyl citrate, respectively), and Creon and Fentanyl citrate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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