Creon and Imdur drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Creon (pancrelipase (amylase;lipase;protease)) and Imdur (isosorbide mononitrate). Common drug interactions include nausea among females and pain among males.
The phase IV clinical study analyzes what interactions people have when they take Creon and Imdur. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.
What is Creon?
Creon has active ingredients of pancrelipase (amylase;lipase;protease). It is often used in pancreatitis. eHealthMe is studying from 29,489 Creon users. Check the latest studies of Creon.
What is Imdur?
Imdur has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 17,367 Imdur users. Check the latest studies of Imdur.
43 people who take Creon and Imdur together, and have interactions are studied.

What are the common drug interactions of Creon and Imdur, by gender? *:
female:
- Nausea (feeling of having an urge to vomit)
- Nervous system disorder (a general class of medical conditions affecting the nervous system)
- Oedema (fluid collection in tissue)
- Oedema peripheral (superficial swelling)
- Pain
- Pancreatic neoplasm (pancreatic tumour)
- Patella fracture
- Procedural complication
- Pruritus (severe itching of the skin)
- Renal disorder (kidney disease)
male:
- Pain
- Pain in extremity
- Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Oedema peripheral (superficial swelling)
- Pleural effusion (water on the lungs)
- Renal disorder (kidney disease)
- Abdominal pain
- Anaemia (lack of blood)
- Anxiety
What are the common drug interactions of Creon and Imdur, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Bradycardia (abnormally slow heart action)
- Cardiomyopathy (weakening of the heart muscle)
- Fall
- Hand fracture
- Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
- Cardiac failure
- Sinus node dysfunction (a group of abnormal heart rhythms)
- Thrombocytopenia (decrease of platelets in blood)
50-59:
- Cholecystitis (infection of gallbladder)
- Death
- Fall
- Impaired healing
- Upper limb fracture
- Weight increased
60+:
- Pain
- Headache (pain in head)
- Oedema peripheral (superficial swelling)
- Renal disorder (kidney disease)
- Dizziness
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Fall
- Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
- Heart rate increased
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
What are the existing conditions these people have? *
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 11.63%
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 9.30%
- Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 4 people, 9.30%
- High Blood Cholesterol: 4 people, 9.30%
- Depression: 4 people, 9.30%
- Cardiac Disorder: 4 people, 9.30%
- Stress And Anxiety: 3 people, 6.98%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 6.98%
* Approximation only. Some reports may have incomplete information.
Do you take Creon and Imdur?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Creon and Imdur:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Creon:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Imdur:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Creon and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Imdur and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on pancrelipase (amylase;lipase;protease) and isosorbide mononitrate (the active ingredients of Creon and Imdur, respectively), and Creon and Imdur (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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