Cresemba and Colace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cresemba (isavuconazonium sulfate) and Colace (docusate ). Common drug interactions include malignant neoplasm progression among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Cresemba and Colace. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Cresemba?

Cresemba has active ingredients of isavuconazonium sulfate. eHealthMe is studying from 2,574 Cresemba users. Check the latest studies of Cresemba.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 15, 2026

50 people who take Cresemba and Colace together, and have interactions are studied.

Cresemba and Colace drug interactions.

What are the common drug interactions of Cresemba and Colace, by gender? *:

female:

  1. Malignant neoplasm progression (cancer tumour came back)
  2. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  3. Mobility decreased (ability to move is reduced)
  4. Nausea (feeling of having an urge to vomit)
  5. Neuropathy peripheral (surface nerve damage)
  6. Obliterative bronchiolitis (bronchiolar inflammation)
  7. Oedema peripheral (superficial swelling)
  8. Palpitations (feelings or sensations that your heart is pounding or racing)
  9. Productive cough
  10. Pyrexia (fever)

male:

  1. Pyrexia (fever)
  2. Hypotension (abnormally low blood pressure)
  3. Blood creatinine increased
  4. Blood lactic acid increased
  5. Blood urea increased
  6. Bone marrow failure
  7. Bradycardia (abnormally slow heart action)
  8. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  9. Cytokine storm (over-protective immune response that can actually be fatal)
  10. Delirium (wild excitement)

What are the common drug interactions of Cresemba and Colace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Septic shock (shock due to blood infection)
  2. Somnolence (a state of near-sleep, a strong desire for sleep)
  3. Staphylococcal infection (an infection with staphylococcus bacteria)
  4. Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
  5. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  6. Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
  7. Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
  8. Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
  9. Blood creatinine increased
  10. Blood lactic acid increased

20-29:

  1. Blood potassium increased
  2. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  3. Dyspnoea (difficult or laboured respiration)
  4. Fluid retention (an abnormal accumulation of fluid in the blood)

30-39:

  1. Cellulitis (infection under the skin)
  2. Neutropenia (an abnormally low number of neutrophils)
  3. Overdose
  4. Upper respiratory tract infection
  5. White blood cell count decreased

40-49:

  1. Blood bilirubin increased
  2. Confusional state
  3. Delirium (wild excitement)
  4. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  5. Eye swelling
  6. Mucormycosis (a rare infection caused by organisms that belong to a group of fungi called mucoromycotina)
  7. Mucosal inflammation (infection of mucous membrane)
  8. Neutropenia (an abnormally low number of neutrophils)
  9. Orbital oedema (swelling of orbit)
  10. Pyrexia (fever)

50-59:

  1. Blood pressure decreased
  2. Cerebral microhaemorrhage (bleeding in brain less than 5 mm in size)
  3. Chest pain
  4. Chronic respiratory failure
  5. Complications of transplanted lung
  6. Diarrhoea
  7. Disease recurrence
  8. Dyspnoea (difficult or laboured respiration)
  9. Encephalomalacia (localized softening of the brain substance, due to haemorrhage or inflammation)
  10. Gait disturbance

60+:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Arthralgia (joint pain)
  3. Nodule (a growth of abnormal tissue)
  4. Pyrexia (fever)
  5. Anaemia (lack of blood)
  6. Respiratory failure (inadequate gas exchange by the respiratory system)
  7. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  8. Apnoea (suspension of external breathing)
  9. Delirium (wild excitement)
  10. Diarrhoea

What are the existing conditions these people have? *

  1. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 17 people, 34.00%
  2. Pain: 9 people, 18.00%
  3. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 7 people, 14.00%
  4. Nausea (feeling of having an urge to vomit): 6 people, 12.00%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 12.00%
  6. Back Pain: 6 people, 12.00%
  7. Acute Lymphocytic Leukaemia Recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent): 5 people, 10.00%
  8. Primary Myelofibrosis (primary disorder of the bone marrow): 4 people, 8.00%
  9. Insomnia (sleeplessness): 4 people, 8.00%
  10. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 4 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Cresemba and Colace?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cresemba and Colace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cresemba:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Colace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cresemba and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Colace and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on isavuconazonium sulfate and docusate (the active ingredients of Cresemba and Colace, respectively), and Cresemba and Colace (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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