Cresemba and Zolpidem drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cresemba (isavuconazonium sulfate) and Zolpidem (zolpidem tartrate). Common drug interactions include death among females and drug-induced liver injury among males.
The phase IV clinical study analyzes what interactions people have when they take Cresemba and Zolpidem. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Cresemba?
Cresemba has active ingredients of isavuconazonium sulfate. eHealthMe is studying from 2,574 Cresemba users. Check the latest studies of Cresemba.
What is Zolpidem?
Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,695 Zolpidem users. Check the latest studies of Zolpidem.
17 people who take Cresemba and Zolpidem together, and have interactions are studied.

What are the common drug interactions of Cresemba and Zolpidem, by gender? *:
female:
- Death
- Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
- Discomfort
- Dyspnoea (difficult or laboured respiration)
- Hot flush (sudden feelings of heat)
- Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
- Hypotension (abnormally low blood pressure)
- Malaise (a feeling of general discomfort or uneasiness)
- Platelet count decreased
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
male:
- Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
- Enterocolitis infectious
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Disease progression
- Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
- Hyperglycaemia (high blood sugar)
- Leukaemia recurrent (repeat cancer of bone marrow or blood cells)
- Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
- Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
- Febrile neutropenia (fever with reduced white blood cells)
What are the common drug interactions of Cresemba and Zolpidem, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
- Aplasia (defective development or congenital absence of an organ or tissue)
- Bacteraemia (presence of bacteria in the blood)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
- Hyperglycaemia (high blood sugar)
- Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
- Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
30-39:
n/a
40-49:
n/a
50-59:
- Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
- Dyspnoea (difficult or laboured respiration)
- Hypotension (abnormally low blood pressure)
- Wheezing (a high-pitched whistling sound made while you breath)
60+:
- Death
- Enterocolitis infectious
- Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
- Malaise (a feeling of general discomfort or uneasiness)
- Platelet count decreased
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Febrile neutropenia (fever with reduced white blood cells)
- Hypocalcaemia (levels of calcium in blood serum are abnormally low)
- Hypokalaemia (low potassium)
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
What are the existing conditions these people have? *
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 7 people, 41.18%
- Necrotising Fasciitis (an uncommon life-threatening soft-tissue infection): 2 people, 11.76%
- Mucormycosis (a rare infection caused by organisms that belong to a group of fungi called mucoromycotina): 2 people, 11.76%
- Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 2 people, 11.76%
- Embolism Venous (embolus may pass into the arterial system): 2 people, 11.76%
- Multiple Myeloma (cancer of the plasma cells): 1 person, 5.88%
- Leukaemia (blood or bone marrow cancer): 1 person, 5.88%
- Itching: 1 person, 5.88%
- High Blood Pressure: 1 person, 5.88%
- Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Cresemba and Zolpidem?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Cresemba and Zolpidem:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cresemba:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zolpidem:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cresemba and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zolpidem and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on isavuconazonium sulfate and zolpidem tartrate (the active ingredients of Cresemba and Zolpidem, respectively), and Cresemba and Zolpidem (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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