Crestor and Adapalene drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Crestor (rosuvastatin calcium) and Adapalene (adapalene). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Crestor and Adapalene. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Crestor?
Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 149,762 Crestor users. Check the latest studies of Crestor.
What is Adapalene?
Adapalene has active ingredients of adapalene. It is often used in acne. eHealthMe is studying from 174,662 Adapalene users. Check the latest studies of Adapalene.
13 people who take Crestor and Adapalene together, and have interactions are studied.

What are the common drug interactions of Crestor and Adapalene, by gender? *:
female:
- Chronic kidney disease
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Skin burning sensation
- Dry skin
- Erythema (redness of the skin)
- Eye irritation
- Overdose
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Pruritus (severe itching of the skin)
male:
- Chronic kidney disease
- Emotional distress
- Spinal fracture (fracture in one of vertebrae)
- Tooth loss
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Atrioventricular block (heart block)
- Atrioventricular dissociation (av block)
- Benign soft tissue neoplasm (benign soft tissue tumour)
- Bradycardia (abnormally slow heart action)
What are the common drug interactions of Crestor and Adapalene, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Atrioventricular block (heart block)
- Atrioventricular dissociation (av block)
- Benign soft tissue neoplasm (benign soft tissue tumour)
- Bradycardia (abnormally slow heart action)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
- Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
- Cardiac failure
- Cardiac failure congestive
- Cardiac output decreased
50-59:
- Dry skin
- Skin burning sensation
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Blood creatinine increased
- Chronic kidney disease
- Emotional distress
- Erythema (redness of the skin)
- Pain
- Renal impairment (severely reduced kidney function)
60+:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Spinal fracture (fracture in one of vertebrae)
- Tooth loss
- Blood creatinine increased
- Death
- Eye irritation
- General physical health deterioration (weak health status)
- Overdose
- Pain of skin
What are the existing conditions these people have? *
- Hiv Infection: 3 people, 23.08%
- Urinary Tract Infection: 1 person, 7.69%
- Stress And Anxiety: 1 person, 7.69%
- Skin Exfoliation (removal of the oldest dead skin cells): 1 person, 7.69%
- Osteoporosis (bones weak and more likely to break): 1 person, 7.69%
- Nausea (feeling of having an urge to vomit): 1 person, 7.69%
- Insomnia (sleeplessness): 1 person, 7.69%
- Infection: 1 person, 7.69%
- Hypersensitivity: 1 person, 7.69%
- Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Crestor and Adapalene?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Crestor and Adapalene:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Crestor:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Adapalene:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Crestor and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Adapalene and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on rosuvastatin calcium and adapalene (the active ingredients of Crestor and Adapalene, respectively), and Crestor and Adapalene (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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