Crestor and Alli drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Crestor (rosuvastatin calcium) and Alli (orlistat). Common drug interactions include muscular weakness among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Crestor and Alli. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Crestor?

Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 149,762 Crestor users. Check the latest studies of Crestor.

What is Alli?

Alli has active ingredients of orlistat. It is often used in weight loss. eHealthMe is studying from 22,818 Alli users. Check the latest studies of Alli.



On Aug, 10, 2026

38 people who take Crestor and Alli together, and have interactions are studied.

Crestor and Alli drug interactions.

What are the common drug interactions of Crestor and Alli, by gender? *:

female:

  1. Muscular weakness (muscle weakness)
  2. Pallor
  3. Pyrexia (fever)
  4. Rectal haemorrhage (bleeding from anus)
  5. Syncope (loss of consciousness with an inability to maintain postural tone)
  6. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  7. Tenderness (pain or discomfort when an affected area is touched)
  8. Tremor (trembling or shaking movements in one or more parts of your body)
  9. Weight increased
  10. Abnormal faeces (abnormal stool)

male:

  1. Cardiac failure congestive
  2. Weight increased
  3. Multiple injuries
  4. Oedema peripheral (superficial swelling)
  5. Sick sinus syndrome (a collection of heart rhythm disorders)
  6. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  7. Blood glucose increased
  8. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  9. Fatigue (feeling of tiredness)
  10. Oesophagitis (inflammation of oesophagus)

What are the common drug interactions of Crestor and Alli, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal pain
  2. Appendicitis (inflammation of the appendix)
  3. Postoperative wound infection

40-49:

  1. Diarrhoea
  2. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  3. Haematochezia (passage of stools containing blood)
  4. Ill-defined disorder

50-59:

  1. Arthralgia (joint pain)
  2. Arthropathy
  3. Atelectasis (partial or complete collapse of the lung)
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  6. Atrioventricular block (heart block)
  7. Back pain
  8. Bartholin's cyst (cyst is formed on one or both of the two bartholin's glands, which are located one on either side of the opening of the vagina)
  9. Blindness
  10. Bone disorder

60+:

  1. Cardiac failure congestive
  2. Weight increased
  3. Colonoscopy
  4. Abdominal pain
  5. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  6. Blood glucose increased
  7. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  8. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  9. Diarrhoea
  10. Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

  1. Multiple Allergies (allergy to multiple agents): 6 people, 15.79%
  2. Cardiac Failure Congestive: 6 people, 15.79%
  3. Migraine (headache): 2 people, 5.26%
  4. Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Crestor and Alli?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Crestor and Alli:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Crestor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Alli:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Crestor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Alli and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on rosuvastatin calcium and orlistat (the active ingredients of Crestor and Alli, respectively), and Crestor and Alli (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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