Crestor and Citrus drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Crestor (rosuvastatin calcium) and Citrus (grapefruit). Common drug interactions include agitation among females and blood pressure increased among males.
The phase IV clinical study analyzes what interactions people have when they take Crestor and Citrus. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Crestor?
Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 149,761 Crestor users. Check the latest studies of Crestor.
What is Citrus?
Citrus has active ingredients of grapefruit. eHealthMe is studying from 201 Citrus users. Check the latest studies of Citrus.
11 people who take Crestor and Citrus together, and have interactions are studied.

What are the common drug interactions of Crestor and Citrus, by gender? *:
female:
- Agitation (state of anxiety or nervous excitement)
- Anxiety
- Bruxism (habitual grinding of the teeth, typically during sleep)
- Confusional state
- Dyspnoea (difficult or laboured respiration)
- Foot deformity (functional disability of foot)
- Haemorrhage (bleeding)
- Malaise (a feeling of general discomfort or uneasiness)
- Nausea (feeling of having an urge to vomit)
- Restlessness (not able to rest)
male:
- Blood pressure increased
- Drug ineffective
- Libido decreased (loss of interest in sex)
- Organic erectile dysfunction (inability to achieve or maintain an erection long enough to engage in sexual intercourse)
- Pruritus (severe itching of the skin)
What are the common drug interactions of Crestor and Citrus, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Bruxism (habitual grinding of the teeth, typically during sleep)
- Confusional state
- Dyspnoea (difficult or laboured respiration)
- Malaise (a feeling of general discomfort or uneasiness)
- Restlessness (not able to rest)
- Snoring
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Tension (the act or process of stretching something tight)
- Tooth fracture
- Abnormal dreams
50-59:
n/a
60+:
- Sinusitis (inflammation of sinus)
- Systemic mycosis (fungal infections of the body)
- Weight decreased
- Drug ineffective
- Haemorrhage (bleeding)
- Libido decreased (loss of interest in sex)
- Organic erectile dysfunction (inability to achieve or maintain an erection long enough to engage in sexual intercourse)
What are the existing conditions these people have? *
- Immunodeficiency Common Variable: 7 people, 63.64%
- Pneumonia Staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus): 1 person, 9.09%
- Platelet Aggregation Inhibition: 1 person, 9.09%
- Gastric Disorder (disease of stomach): 1 person, 9.09%
- Blood Testosterone Decreased: 1 person, 9.09%
- Bipolar Disorder (mood disorder): 1 person, 9.09%
- B-Lymphocyte Abnormalities (abnormal population of b lymphocytes in the blood, bone marrow, or tissues): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Crestor and Citrus?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Crestor and Citrus:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Crestor:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Citrus:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Crestor and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Citrus and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on rosuvastatin calcium and grapefruit (the active ingredients of Crestor and Citrus, respectively), and Crestor and Citrus (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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