Crestor and Purinethol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Crestor (rosuvastatin calcium) and Purinethol (mercaptopurine). Common drug interactions include fatigue among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Crestor and Purinethol. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Crestor?

Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 149,762 Crestor users. Check the latest studies of Crestor.

What is Purinethol?

Purinethol has active ingredients of mercaptopurine. It is often used in ulcerative colitis. eHealthMe is studying from 3,810 Purinethol users. Check the latest studies of Purinethol.

On Jul, 31, 2026

29 people who take Crestor and Purinethol together, and have interactions are studied.

Crestor and Purinethol drug interactions.

What are the common drug interactions of Crestor and Purinethol, by gender? *:

female:

Fatigue (feeling of tiredness)
Nasopharyngitis (inflammation of the nasopharynx)
Pleural effusion (water on the lungs)
Sinusitis (inflammation of sinus)
Adverse event
Dysphonia (speech disorder attributable to a disorder of phonation)
Hot flush (sudden feelings of heat)
Infusion related reaction
Ocular hyperaemia (an abnormally large amount of blood in eye)
Oxygen saturation decreased

male:

Diarrhoea
Blood creatinine increased
Amylase increased
Bence jones proteinuria (immunoglobulin light chain found in the urine)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Inflammation
Lipase increased
Lymphopenia (an abnormally low level of lymphocytes in the blood)
Polyarthritis (arthritis which involves 5 or more joints simultaneously)

What are the common drug interactions of Crestor and Purinethol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Spinal compression fracture (fracture due to spinal compression on bone)
Spinal fracture (fracture in one of vertebrae)
Spinal osteoarthritis (joint cartilage loss in spine)
Thrombosis (formation of a blood clot inside a blood vessel)
Colonic stenosis (abnormal narrowing of colon)
Constipation
Frequent bowel movements
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Intestinal obstruction
Vitamin b12 decreased

50-59:

Metastases to liver (cancer spreads to liver)
Drug level increased
Fatigue (feeling of tiredness)
Hepatic enzyme increased
Poor peripheral circulation

60+:

Diarrhoea
Fatigue (feeling of tiredness)
Dysphonia (speech disorder attributable to a disorder of phonation)
Gamma-glutamyltransferase increased
Hot flush (sudden feelings of heat)
Hunger
Infusion related reaction
Intestinal resection
Ocular hyperaemia (an abnormally large amount of blood in eye)
Oxygen saturation decreased

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 12 people, 41.38%
High Blood Pressure: 4 people, 13.79%
Depression: 4 people, 13.79%
Stress And Anxiety: 3 people, 10.34%
Productive Cough: 3 people, 10.34%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 10.34%
Cardiac Failure: 3 people, 10.34%
Mitral Valve Incompetence (inefficient heart valve): 2 people, 6.90%
Laxative Supportive Care: 2 people, 6.90%
Gastric Disorder (disease of stomach): 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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