Crestor and Sirolimus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Crestor (rosuvastatin calcium) and Sirolimus (sirolimus). Common drug interactions include peripheral swelling among females and blood creatinine increased among males.

The phase IV clinical study analyzes what interactions people have when they take Crestor and Sirolimus. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Crestor?

Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 149,761 Crestor users. Check the latest studies of Crestor.

What is Sirolimus?

Sirolimus has active ingredients of sirolimus. eHealthMe is studying from 11,823 Sirolimus users. Check the latest studies of Sirolimus.

On Jul, 08, 2026

49 people who take Crestor and Sirolimus together, and have interactions are studied.

Crestor and Sirolimus drug interactions.

What are the common drug interactions of Crestor and Sirolimus, by gender? *:

female:

Peripheral swelling
Swelling face
Abdominal pain
Back pain
Infection
Pyrexia (fever)
Vomiting
Aphthous ulcer (mouth ulcer)
Asthenia (weakness)
Conjunctivitis (pink eye)

male:

Blood creatinine increased
Dyspnoea (difficult or laboured respiration)
Decreased appetite
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dyspnoea exertional (breathlessness or shortness of breath)
Fall
Graft versus host disease in skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin)
Malaise (a feeling of general discomfort or uneasiness)
Muscular weakness (muscle weakness)
Pancreatitis (inflammation of pancreas)

What are the common drug interactions of Crestor and Sirolimus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain
Burning sensation
Candida sepsis (candida in blood stream)
Colitis (inflammation of colon)
Coma (state of unconsciousness lasting more than six hours)
Cystitis haemorrhagic (blood in the urine and painful voiding)
Cytomegalovirus infection
Diarrhoea
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Gastrointestinal obstruction

40-49:

Stent placement

50-59:

Dyspnoea (difficult or laboured respiration)
Generalised oedema (swelling all over the body)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Pancreatitis (inflammation of pancreas)
Bone marrow transplant rejection
Death
Low density lipoprotein increased (cholesterol increased in blood)
Oedema peripheral (superficial swelling)
Pruritus (severe itching of the skin)
Pulmonary oedema (fluid accumulation in the lungs)

60+:

Malaise (a feeling of general discomfort or uneasiness)
Diarrhoea
Swelling
Drug ineffective
Abdominal pain
Arthralgia (joint pain)
Back pain
Brain natriuretic peptide increased
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)

What are the existing conditions these people have? *

High Blood Pressure: 11 people, 22.45%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 8 people, 16.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 12.24%
Immunodeficiency Disorders: 5 people, 10.20%
Diabetes: 5 people, 10.20%
Oedema (fluid collection in tissue): 4 people, 8.16%
Lymphangioleiomyomatosis (a rare lung condition that affects a certain type of muscle cell and only occurs in women): 4 people, 8.16%
Blood Pressure Abnormal: 4 people, 8.16%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 6.12%
Cellulitis (infection under the skin): 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

Do you take Crestor and Sirolimus?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously