Crestor and Vicoprofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Crestor (rosuvastatin calcium) and Vicoprofen (hydrocodone bitartrate; ibuprofen). Common drug interactions include sinus bradycardia among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Crestor and Vicoprofen. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Crestor?

Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 149,762 Crestor users. Check the latest studies of Crestor.

What is Vicoprofen?

Vicoprofen has active ingredients of hydrocodone bitartrate; ibuprofen. It is often used in pain. eHealthMe is studying from 1,842 Vicoprofen users. Check the latest studies of Vicoprofen.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 16, 2026

40 people who take Crestor and Vicoprofen together, and have interactions are studied.

Crestor and Vicoprofen drug interactions.

What are the common drug interactions of Crestor and Vicoprofen, by gender? *:

female:

Sinus bradycardia (an unusually slow heartbeat due to heart disease)
Splinter haemorrhages (tiny blood clots that tend to run vertically under the nails)
Vasculitis (inflammation of a blood vessel or blood vessels)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Abdominal distension
Acute myocardial infarction (acute heart attack)
Chest pain
Cough
Discomfort
Eye pruritus (eye itching)

male:

Abdominal pain
Migraine (headache)
Dyspnoea (difficult or laboured respiration)
Hemiplegia (paralysis of one side of the body)
Leukocytosis (increased white blood cells)
Muscle atrophy (a decrease in the mass of the muscle)
Pneumonia
Renal failure (kidney dysfunction)
Streptococcal sepsis (whole body inflammation by streptococcal)
Thrombocytopenia (decrease of platelets in blood)

What are the common drug interactions of Crestor and Vicoprofen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Asthenia (weakness)
Chronic kidney disease
Disability
Drug hypersensitivity
Drug ineffective
Emotional disorder
Muscle atrophy (a decrease in the mass of the muscle)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Myalgia (muscle pain)
Nephrogenic anaemia (anaemia due to kidney disease)

50-59:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Ocular vascular disorder (disease of eye blood circulation)
Optic atrophy (the loss of a proportion of optic disc nerve fibres)
Optic nerve disorder (disease of optic nerve)
Osteopenia (a condition where bone mineral density is lower than normal)
Pneumonia
Postmenopausal haemorrhage (post-menopausal bleeding)
Scar
Sinus congestion (blockage of sinus)
Streptococcal sepsis (whole body inflammation by streptococcal)

60+:

Abdominal distension
Asthenia (weakness)
Abdominal pain
Balance disorder
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Body temperature increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure
Chills (felling of cold)
Confusional state

What are the existing conditions these people have? *

Insomnia (sleeplessness): 4 people, 10.00%
Diabetes: 4 people, 10.00%
Neuralgia (pain in one or more nerves): 3 people, 7.50%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 7.50%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 7.50%
Asthma: 3 people, 7.50%
Type 2 Diabetes: 2 people, 5.00%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 5.00%
Multiple Myeloma (cancer of the plasma cells): 2 people, 5.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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