Crixivan and Neupogen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Crixivan (indinavir sulfate) and Neupogen (filgrastim). Common drug interactions include crystal urine present among females and diplopia among males.

The phase IV clinical study analyzes what interactions people have when they take Crixivan and Neupogen. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Crixivan?

Crixivan has active ingredients of indinavir sulfate. eHealthMe is studying from 6,312 Crixivan users. Check the latest studies of Crixivan.

What is Neupogen?

Neupogen has active ingredients of filgrastim. It is often used in agranulocytosis. eHealthMe is studying from 23,898 Neupogen users. Check the latest studies of Neupogen.

On Jul, 10, 2026

44 people who take Crixivan and Neupogen together, and have interactions are studied.

Crixivan and Neupogen drug interactions.

What are the common drug interactions of Crixivan and Neupogen, by gender? *:

female:

Crystal urine present
Haematocrit decreased
Haemoglobin decreased
Haemolytic anaemia (anaemia due to haemolysis)
Nephrolithiasis (calculi in the kidneys)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Protein urine present
Urine leukocyte esterase positive
Uveitis (inflammation of the uvea)
White blood cells urine positive

male:

Diplopia (double vision)
Eyelid ptosis (falling of the upper or lower eyelid)
Anaemia (lack of blood)
Blood creatinine increased
Colitis pseudomembranous (antibiotic-associated diarrhoea)
Dyspnoea (difficult or laboured respiration)
Extraocular muscle paresis (nerve paralysis outside of eye tissue)
Haematocrit decreased
Ophthalmoplegia (a paralysis or weakness of one or more of the muscles that control eye movement)
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Crixivan and Neupogen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Haematuria present (presence of blood in urine due to trauma)
Loin pain (pain originates from kidney)
Pyelonephritis (inflammation of kidney caused by bacteria)
Pyrexia (fever)
Renal disorder (kidney disease)
Urinary tract infection enterococcal

10-19:

n/a

20-29:

Headache (pain in head)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Extradural haematoma (traumatic brain injury-collection of blood in the 'potential' space between the skull and the outer protective)
Femoral neck fracture (neck of femur bone fracture)
Pyrexia (fever)
Subdural haematoma (blood collects between the skull and the surface of the brain)

30-39:

Blood creatinine increased
Blood in stool
Bowel sounds
Cholecystitis (infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Colitis (inflammation of colon)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Diverticulitis intestinal (digestive disease which involves the formation of pouches (diverticula) within the intestinal wall)
Haemolytic anaemia (anaemia due to haemolysis)
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)

40-49:

Dyspnoea (difficult or laboured respiration)
Anaemia (lack of blood)
Cellulitis (infection under the skin)
Fatigue (feeling of tiredness)
Kaposi's sarcoma (a tumour caused by human herpes virus)
Oedema lower limb (fluid collection in tissue of lower leg)
Abdominal distension
Haematocrit decreased
Oedema (fluid collection in tissue)
Pyrexia (fever)

50-59:

Blood creatinine increased
Optic neuritis (optic nerve inflammation)
Hydronephrosis (water inside the kidney)
Microangiopathy (disease of the capillaries (very small blood vessels), in which the capillary walls become so thick and weak that they bleed, leak protein)
Nausea (feeling of having an urge to vomit)
Optic neuropathy (optic nerve damage)
Pneumonia
Renal impairment (severely reduced kidney function)
Thrombocytopenia (decrease of platelets in blood)
Urinary tract obstruction

60+:

n/a

What are the existing conditions these people have? *

Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 3 people, 6.82%
Ill-Defined Disorder: 3 people, 6.82%
Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

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