Cubicin and Nystatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cubicin (daptomycin) and Nystatin (nystatin). Common drug interactions include hypoglycaemia among females and cardiac arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Cubicin and Nystatin. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Cubicin?

Cubicin has active ingredients of daptomycin. It is often used in infection. eHealthMe is studying from 7,991 Cubicin users. Check the latest studies of Cubicin.

What is Nystatin?

Nystatin has active ingredients of nystatin. It is often used in thrush. eHealthMe is studying from 33,567 Nystatin users. Check the latest studies of Nystatin.



On Jul, 09, 2026

39 people who take Cubicin and Nystatin together, and have interactions are studied.

Cubicin and Nystatin drug interactions.

What are the common drug interactions of Cubicin and Nystatin, by gender? *:

female:

  1. Hypoglycaemia (deficiency of glucose in the bloodstream)
  2. Hypokalaemia (low potassium)
  3. Hypotension (abnormally low blood pressure)
  4. Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
  5. Ill-defined disorder
  6. Increased viscosity of bronchial secretion
  7. Injury
  8. Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
  9. Lethargy (tiredness)
  10. Malaise (a feeling of general discomfort or uneasiness)

male:

  1. Cardiac arrest
  2. Hyperkalaemia (damage to or disease of the kidney)
  3. Atrioventricular block second degree (heart block second degree)
  4. Bacteria urine identified
  5. Blood chloride decreased
  6. Blood creatine phosphokinase increased
  7. Blood creatine phosphokinase mb increased
  8. Blood sodium decreased
  9. Blood urea increased
  10. Bradycardia (abnormally slow heart action)

What are the common drug interactions of Cubicin and Nystatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Cellulitis (infection under the skin)
  2. Eosinophilia (eosinophil count in the peripheral blood exceeds)

40-49:

  1. Dysgeusia (disorder of the sense of taste)
  2. Muscle twitching
  3. Arthralgia (joint pain)
  4. Chondromalacia (anterior knee pain due to irritation of the cartilage on the under surface of the kneecap)
  5. Device related infection
  6. Diarrhoea
  7. Dyspnoea (difficult or laboured respiration)
  8. Fatigue (feeling of tiredness)
  9. Fistula (an abnormal connection or passageway between two)
  10. Iron deficiency anaemia

50-59:

  1. Pseudomonal bacteraemia (p. aeruginosa cause of bacterial infections of the blood)
  2. Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
  3. Pulmonary hypertension (increase in blood pressure in the lung artery)
  4. Pulseless electrical activity
  5. Pyrexia (fever)
  6. Pyuria (a condition of urine containing pus)
  7. Rales (an abnormal respiratory sound characterized by fine crackles)
  8. Renal failure acute (rapid kidney dysfunction)
  9. Anaemia (lack of blood)
  10. Dyspnoea (difficult or laboured respiration)

60+:

  1. International normalised ratio increased
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  3. Blood calcium increased
  4. Blood chloride decreased
  5. Blood sodium decreased
  6. Bradycardia (abnormally slow heart action)
  7. Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
  8. Dislocation of joint prosthesis
  9. Femur fracture
  10. Haematocrit decreased

What are the existing conditions these people have? *

  1. Staphylococcal Infection (an infection with staphylococcus bacteria): 6 people, 15.38%
  2. Staphylococcal Bacteraemia (a bacterial infection of blood): 4 people, 10.26%
  3. Device Related Infection: 4 people, 10.26%
  4. Radiation Pneumonitis (inflammation of lung due to radiation): 3 people, 7.69%
  5. Pulmonary Embolism (blockage of the main artery of the lung): 3 people, 7.69%
  6. Iron Deficiency Anaemia: 3 people, 7.69%
  7. High Blood Pressure: 3 people, 7.69%
  8. Depression: 3 people, 7.69%
  9. Breast Cancer Stage Iii: 3 people, 7.69%
  10. Breast Cancer Metastatic: 3 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Cubicin and Nystatin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cubicin and Nystatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cubicin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nystatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cubicin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nystatin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on daptomycin and nystatin (the active ingredients of Cubicin and Nystatin, respectively), and Cubicin and Nystatin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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