Cyclophosphamide and Vytorin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cyclophosphamide (cyclophosphamide) and Vytorin (ezetimibe; simvastatin). Common drug interactions include asthenia among females and sepsis among males.

The phase IV clinical study analyzes what interactions people have when they take Cyclophosphamide and Vytorin. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Cyclophosphamide?

Cyclophosphamide has active ingredients of cyclophosphamide. It is often used in multiple myeloma. eHealthMe is studying from 185,240 Cyclophosphamide users. Check the latest studies of Cyclophosphamide.

What is Vytorin?

Vytorin has active ingredients of ezetimibe; simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 20,084 Vytorin users. Check the latest studies of Vytorin.

On Jul, 13, 2026

53 people who take Cyclophosphamide and Vytorin together, and have interactions are studied.

Cyclophosphamide and Vytorin drug interactions.

What are the common drug interactions of Cyclophosphamide and Vytorin, by gender? *:

female:

Asthenia (weakness)
Insomnia (sleeplessness)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Platelet count decreased
Pneumonia
Renal failure acute (rapid kidney dysfunction)
Thrombocytopenia (decrease of platelets in blood)
White blood cell count decreased
Alopecia (absence of hair from areas of the body)
Arthralgia (joint pain)

male:

Sepsis (a severe blood infection that can lead to organ failure and death)
Neutropenia (an abnormally low number of neutrophils)
Nausea (feeling of having an urge to vomit)
Vomiting
Abdominal abscess (collection of pus in abdomen)
Blood culture positive
Colonic obstruction (obstruction in colon)
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)

What are the common drug interactions of Cyclophosphamide and Vytorin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Febrile neutropenia (fever with reduced white blood cells)
Obesity (having too much body fat)
Type 2 diabetes mellitus

50-59:

Abdominal pain upper
Abscess limb (limb infection)
Adrenal adenoma (benign tumour of the glandular type (adenoma) in the adrenal gland)
Anaemia (lack of blood)
Ankle fracture
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic dilatation
Aortic valve incompetence
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)

60+:

Death
Pneumonia
Blood culture positive
Colonic obstruction (obstruction in colon)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Enterococcal infection
Fungal infection
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)

What are the existing conditions these people have? *

Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 8 people, 15.09%
High Blood Pressure: 8 people, 15.09%
Febrile Neutropenia (fever with reduced white blood cells): 5 people, 9.43%
Dyslipidaemia (abnormal amount of lipids): 5 people, 9.43%
Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 4 people, 7.55%
Breast Cancer: 4 people, 7.55%
Bipolar Disorder (mood disorder): 4 people, 7.55%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 7.55%
Jc Virus Test Positive: 3 people, 5.66%
Diabetes: 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

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