Cylert and Synthroid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cylert (pemoline) and Synthroid (levothyroxine sodium). Common drug interactions include chest pain among females and neoplasm among males.

The phase IV clinical study analyzes what interactions people have when they take Cylert and Synthroid. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Cylert?

Cylert has active ingredients of pemoline. eHealthMe is studying from 785 Cylert users. Check the latest studies of Cylert.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,198 Synthroid users. Check the latest studies of Synthroid.

On Jul, 20, 2026

33 people who take Cylert and Synthroid together, and have interactions are studied.

What are the common drug interactions of Cylert and Synthroid, by gender? *:

female:

Chest pain
Depression
Gastro-oesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Injection site reaction
Accident
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cardiac disorder
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Constipation
Cough

male:

Neoplasm (tumour)
Nocturia (the need to get up in the night to urinate)
Pruritus (severe itching of the skin)

What are the common drug interactions of Cylert and Synthroid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Thrombocytopenia (decrease of platelets in blood)

20-29:

n/a

30-39:

Influenza like illness
Injection site haemorrhage (bleeding from injection site)
Injection site pain
Post procedural complication
Self mutilation
Skin lesion
Suicide attempt
Tinnitus (a ringing in the ears)
Depression
Accident

40-49:

Injection site pain
Enzyme abnormality
Glossitis (infection of tongue with soreness)
Haemorrhage (bleeding)
Injection site inflammation
Injection site reaction
Skin disorder (skin disease)
Tongue disorder (disease of tongue)
Tongue oedema (swelling of tongue)
Uveitis (inflammation of the uvea)

50-59:

Dyspnoea (difficult or laboured respiration)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Chest pain
Gastro-oesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Asthma
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Cough
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Upper respiratory tract infection

60+:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Asthma
Retinal vein thrombosis (clot formation in small veins that carry blood away from the retina)
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombocytopenia (decrease of platelets in blood)
Thromboembolism (obstruction of artery by blood clot)
Tremor (trembling or shaking movements in one or more parts of your body)
Confusional state
Drug maladministration
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)

What are the existing conditions these people have? *

Pain: 2 people, 6.06%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 6.06%
Depression: 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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