Cymbalta and Kalbitor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cymbalta (duloxetine hydrochloride) and Kalbitor (ecallantide). Common drug interactions include hereditary angioedema among females and respiratory syncytial virus infection among males.

The phase IV clinical study analyzes what interactions people have when they take Cymbalta and Kalbitor. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Cymbalta?

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. eHealthMe is studying from 154,973 Cymbalta users. Check the latest studies of Cymbalta.

What is Kalbitor?

Kalbitor has active ingredients of ecallantide. eHealthMe is studying from 2,079 Kalbitor users. Check the latest studies of Kalbitor.



On Jul, 05, 2026

29 people who take Cymbalta and Kalbitor together, and have interactions are studied.

Cymbalta and Kalbitor drug interactions.

What are the common drug interactions of Cymbalta and Kalbitor, by gender? *:

female:

  1. Hereditary angioedema (recurrent episodes of severe swelling)
  2. Diarrhoea
  3. Dyspepsia (indigestion)
  4. Ear congestion
  5. Gait disturbance
  6. Hypoaesthesia (reduced sense of touch or sensation)
  7. Influenza
  8. Nausea (feeling of having an urge to vomit)
  9. Pain
  10. Pyrexia (fever)

male:

  1. Respiratory syncytial virus infection (viral disease of respiratory system)

What are the common drug interactions of Cymbalta and Kalbitor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Anaphylactic reaction (serious allergic reaction)
  2. Hereditary angioedema (recurrent episodes of severe swelling)

20-29:

  1. Asthenia (weakness)
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Dyspepsia (indigestion)
  4. Fall
  5. Gait disturbance
  6. Hypoaesthesia (reduced sense of touch or sensation)
  7. Influenza
  8. Loss of consciousness
  9. Rash pustular (redness with pustules)
  10. Skin reaction

30-39:

n/a

40-49:

  1. Abdominal discomfort
  2. Anaphylactic reaction (serious allergic reaction)
  3. Angioedema (rapid swelling of the dermis)
  4. Infection
  5. Vasoconstriction (constriction of blood vessels, which increases blood pressure)
  6. Abdominal pain lower
  7. Diarrhoea

50-59:

  1. Hereditary angioedema (recurrent episodes of severe swelling)
  2. Oropharyngeal discomfort (pain or irritation of oropharynx)
  3. Blood glucose increased
  4. Diarrhoea
  5. Ear congestion
  6. Immune system disorder
  7. Nausea (feeling of having an urge to vomit)
  8. Pain
  9. Pyrexia (fever)
  10. Rash

60+:

  1. Hereditary angioedema (recurrent episodes of severe swelling)
  2. Loss of consciousness
  3. Femur fracture
  4. Haematoma (collection of blood outside the blood vessels)
  5. Nodule (a growth of abnormal tissue)
  6. Oxygen saturation decreased
  7. Pruritus (severe itching of the skin)
  8. Speech disorder
  9. Swelling
  10. Tooth fracture

What are the existing conditions these people have? *

  1. Hereditary Angioedema (recurrent episodes of severe swelling): 25 people, 86.21%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 17.24%
  3. High Blood Pressure: 4 people, 13.79%
  4. Asthma: 4 people, 13.79%
  5. Stress And Anxiety: 3 people, 10.34%
  6. Migraine (headache): 3 people, 10.34%
  7. Immune System Disorder: 3 people, 10.34%
  8. High Blood Cholesterol: 3 people, 10.34%
  9. Parkinson's Disease: 2 people, 6.90%
  10. Nausea (feeling of having an urge to vomit): 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

Do you take Cymbalta and Kalbitor?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cymbalta and Kalbitor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cymbalta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Kalbitor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cymbalta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Kalbitor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on duloxetine hydrochloride and ecallantide (the active ingredients of Cymbalta and Kalbitor, respectively), and Cymbalta and Kalbitor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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