Cytarabine and Sublimaze drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cytarabine (cytarabine) and Sublimaze (fentanyl citrate). Common drug interactions include febrile neutropenia among females and drug-induced liver injury among males.

The phase IV clinical study analyzes what interactions people have when they take Cytarabine and Sublimaze. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Cytarabine?

Cytarabine has active ingredients of cytarabine. It is often used in acute myelogenous leukemia (aml) - adult. eHealthMe is studying from 65,358 Cytarabine users. Check the latest studies of Cytarabine.

What is Sublimaze?

Sublimaze has active ingredients of fentanyl citrate. eHealthMe is studying from 560 Sublimaze users. Check the latest studies of Sublimaze.

On Jul, 13, 2026

16 people who take Cytarabine and Sublimaze together, and have interactions are studied.

Cytarabine and Sublimaze drug interactions.

What are the common drug interactions of Cytarabine and Sublimaze, by gender? *:

female:

Febrile neutropenia (fever with reduced white blood cells)
Fungaemia (fungi circulate in the blood)
Neutropenic colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition)
Respiratory failure (inadequate gas exchange by the respiratory system)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Blood creatinine increased
Cardiac ventricular disorder (ventricular dysfunction of heart)
Conduction disorder (serious disorder of the heart not responses proper to impulses)
Constipation
Culture urine positive

male:

Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Sepsis (a severe blood infection that can lead to organ failure and death)
Pneumonia
Pulmonary oedema (fluid accumulation in the lungs)
Respiratory distress (difficulty in breathing)
Blood bilirubin increased
Bone marrow failure
Cardiomegaly (increased size of heart than normal)
Flatulence (flatus expelled through the anus)
Hydronephrosis (water inside the kidney)

What are the common drug interactions of Cytarabine and Sublimaze, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Blood creatinine increased
Cardiac ventricular disorder (ventricular dysfunction of heart)
Conduction disorder (serious disorder of the heart not responses proper to impulses)
Constipation
Culture urine positive
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Electrocardiogram st-t change
Enterococcal infection

50-59:

Febrile neutropenia (fever with reduced white blood cells)
Fungaemia (fungi circulate in the blood)
Neutropenic colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition)
Respiratory failure (inadequate gas exchange by the respiratory system)
Stomatitis (inflammation of mucous membrane of mouth)

60+:

Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Sepsis (a severe blood infection that can lead to organ failure and death)
Pulmonary oedema (fluid accumulation in the lungs)
Respiratory distress (difficulty in breathing)
Blood bilirubin increased
Bone marrow failure
Cardiomegaly (increased size of heart than normal)
Flatulence (flatus expelled through the anus)
Hydronephrosis (water inside the kidney)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 14 people, 87.50%
Pain: 5 people, 31.25%
Infection: 4 people, 25.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 25.00%
Dyspnea (difficult or laboured breathing): 4 people, 25.00%
Fever: 4 people, 25.00%
High Blood Pressure: 4 people, 25.00%
Hypokalemia (low potassium): 4 people, 25.00%
Insomnia (sleeplessness): 4 people, 25.00%
Constipation: 4 people, 25.00%

* Approximation only. Some reports may have incomplete information.

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