D-ribose and Melatonin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take D-ribose (ribose) and Melatonin (melatonin). Common drug interactions include quality of life decreased among females and abasia among males.

The phase IV clinical study analyzes what interactions people have when they take D-ribose and Melatonin. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is D-ribose?

D-ribose has active ingredients of ribose. eHealthMe is studying from 109 D-ribose users. Check the latest studies of D-ribose.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.

On Jul, 13, 2026

16 people who take D-ribose and Melatonin together, and have interactions are studied.

D-ribose and Melatonin drug interactions.

What are the common drug interactions of D-Ribose and Melatonin, by gender? *:

female:

Quality of life decreased
Scoliosis (a medical condition in which a person's spine is curved from side to side)
Sinusitis (inflammation of sinus)
Skin exfoliation (removal of the oldest dead skin cells)
Spinal osteoarthritis (joint cartilage loss in spine)
Suicidal ideation
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Temperature regulation disorder (body is unable to maintain temperature)
Tendon disorder (disease of tendon)
Therapeutic response decreased (less preventive response)

male:

Abasia (inability to walk)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Fatigue (feeling of tiredness)
Fibromyalgia (a long-term condition which causes pain all over the body)
Headache (pain in head)
Hyperacusis (disorder in loudness perception)
Hyperhidrosis (abnormally increased sweating)
Hypoaesthesia (reduced sense of touch or sensation)
Libido decreased (loss of interest in sex)
Lymphadenopathy (disease or enlargement of lymph nodes)

What are the common drug interactions of D-Ribose and Melatonin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Ill-defined disorder
Impaired gastric emptying
Impaired work ability
Inflammation
Irritability
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Muscular weakness (muscle weakness)
Neuropathy peripheral (surface nerve damage)
Quality of life decreased

50-59:

Anxiety
Abasia (inability to walk)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Back pain
Depression
Dizziness
Dyspnoea (difficult or laboured respiration)
Eye irritation

60+:

Arthralgia (joint pain)
Depression
Asthenia (weakness)
Blood glucose increased
Bone pain
Diplopia (double vision)
Dysstasia (difficulty in standing)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Fall
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 37.50%
Pain: 3 people, 18.75%
Osteoporosis (bones weak and more likely to break): 2 people, 12.50%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 12.50%
Stress And Anxiety: 1 person, 6.25%
Respiratory Tract Infection: 1 person, 6.25%
Muscle Aches (muscle pain): 1 person, 6.25%
Depression: 1 person, 6.25%
Concussion (short loss of normal brain function in response to a head injury): 1 person, 6.25%
Colon Cancer Metastatic (cancer of colon spreads to other part of body): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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