Prednisolone and Rufen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prednisolone (prednisolone) and Rufen (ibuprofen). Common drug interactions include diverticulitis among females and rash among males.

The phase IV clinical study analyzes what interactions people have when they take Prednisolone and Rufen. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Prednisolone?

Prednisolone has active ingredients of prednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 212,675 Prednisolone users. Check the latest studies of Prednisolone.

What is Rufen?

Rufen has active ingredients of ibuprofen. eHealthMe is studying from 205 Rufen users. Check the latest studies of Rufen.

On Jul, 13, 2026

14 people who take Prednisolone and Rufen together, and have interactions are studied.

Prednisolone and Rufen drug interactions.

What are the common drug interactions of Prednisolone and Rufen, by gender? *:

female:

Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Ear disorder
Hypertension (high blood pressure)
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Infection
Neutropenia (an abnormally low number of neutrophils)
Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon)
Pyrexia (fever)
Epstein-barr virus infection
Gastrointestinal disorder (functional problems of gastrointestinal tract)

male:

Rash
Arthralgia (joint pain)
Joint range of motion decreased (disease of joint movement)
Skin disorder (skin disease)

What are the common drug interactions of Prednisolone and Rufen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Epstein-barr virus infection
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Neutropenia (an abnormally low number of neutrophils)

10-19:

Arthralgia (joint pain)
Joint range of motion decreased (disease of joint movement)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hypoaesthesia (reduced sense of touch or sensation)
Lymphocyte count decreased

60+:

Rash
Cytomegalovirus infection
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Hypertension (high blood pressure)
Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon)
Pyrexia (fever)
Skin disorder (skin disease)

What are the existing conditions these people have? *

Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 4 people, 28.57%
High Blood Pressure: 4 people, 28.57%
Arrhythmias (irregular heartbeat): 4 people, 28.57%
Dyslipidaemia (abnormal amount of lipids): 4 people, 28.57%
Febrile Neutropenia (fever with reduced white blood cells): 4 people, 28.57%
Neuropathy Peripheral (surface nerve damage): 4 people, 28.57%
Herpes Simplex (herpes simplex is a common viral infection): 4 people, 28.57%
Adult T-Cell Lymphoma/leukaemia (cancer of the immune system's own t-cells): 4 people, 28.57%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 3 people, 21.43%
Histiocytosis Haematophagic: 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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