Daklinza and Tacrolimus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Daklinza (daclatasvir dihydrochloride) and Tacrolimus (tacrolimus). Common drug interactions include fatigue among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Daklinza and Tacrolimus. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Daklinza?

Daklinza has active ingredients of daclatasvir dihydrochloride. eHealthMe is studying from 3,312 Daklinza users. Check the latest studies of Daklinza.

What is Tacrolimus?

Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,160 Tacrolimus users. Check the latest studies of Tacrolimus.



On Jul, 10, 2026

27 people who take Daklinza and Tacrolimus together, and have interactions are studied.

Daklinza and Tacrolimus drug interactions.

What are the common drug interactions of Daklinza and Tacrolimus, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Listless (lack of interest, energy, or spirit)
  3. Thrombosis (formation of a blood clot inside a blood vessel)
  4. Back pain
  5. Calciphylaxis (is a syndrome with vascular calcium accumulation)
  6. Acute respiratory distress syndrome
  7. Acute respiratory failure
  8. Asthenia (weakness)
  9. Bradycardia (abnormally slow heart action)
  10. Brain compression

male:

  1. Anaemia (lack of blood)
  2. Asthenia (weakness)
  3. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  4. Genotype drug resistance test positive
  5. Heart transplant
  6. Hypoglycaemia (deficiency of glucose in the bloodstream)
  7. Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
  8. Lower respiratory tract infection
  9. Lymphopenia (an abnormally low level of lymphocytes in the blood)
  10. Occult blood positive

What are the common drug interactions of Daklinza and Tacrolimus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Fatigue (feeling of tiredness)
  2. Listless (lack of interest, energy, or spirit)
  3. Thrombosis (formation of a blood clot inside a blood vessel)
  4. Calciphylaxis (is a syndrome with vascular calcium accumulation)
  5. Heart transplant
  6. Lethargy (tiredness)
  7. Skin lesion
  8. Skin ulcer

50-59:

  1. Back pain
  2. Dehydration (dryness resulting from the removal of water)
  3. Diarrhoea
  4. Fatigue (feeling of tiredness)
  5. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  6. Genotype drug resistance test positive
  7. Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
  8. Neutropenia (an abnormally low number of neutrophils)
  9. Pain
  10. Pancreatitis acute (sudden inflammation of pancreas)

60+:

  1. Anaemia (lack of blood)
  2. Asthenia (weakness)
  3. Death
  4. Depressed level of consciousness
  5. Erythema nodosum (skin inflammation that results in reddish, painful, tender lumps most commonly located in the front of the legs below)
  6. Fatigue (feeling of tiredness)
  7. Hypertensive hydrocephalus (abnormal expansion of cavities (ventricles) within the brain that is caused by high blood pressure)
  8. Hypoglycaemia (deficiency of glucose in the bloodstream)
  9. Influenza
  10. Lower respiratory tract infection

What are the existing conditions these people have? *

  1. Hepatitis C: 17 people, 62.96%
  2. High Blood Pressure: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Daklinza and Tacrolimus?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Daklinza and Tacrolimus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Daklinza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tacrolimus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Daklinza and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tacrolimus and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on daclatasvir dihydrochloride and tacrolimus (the active ingredients of Daklinza and Tacrolimus, respectively), and Daklinza and Tacrolimus (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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