Diflucan and Apixaban drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diflucan (fluconazole) and Apixaban (apixaban). Common drug interactions include cardiac failure among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Diflucan and Apixaban. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Diflucan?

Diflucan has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 28,471 Diflucan users. Check the latest studies of Diflucan.

What is Apixaban?

Apixaban has active ingredients of apixaban. It is often used in blood clots. eHealthMe is studying from 60,351 Apixaban users. Check the latest studies of Apixaban.

On Jul, 10, 2026

24 people who take Diflucan and Apixaban together, and have interactions are studied.

Diflucan and Apixaban drug interactions.

What are the common drug interactions of Diflucan and Apixaban, by gender? *:

female:

Cardiac failure
Disease progression
Pneumonia
Depression
Pain
Anxiety
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Chronic kidney disease
Clostridium colitis (inflammation of colon by clostridium difficile bacteria infection)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Dyspnoea (difficult or laboured respiration)
Fall
Head injury
Hospitalisation
Pneumonia
Renal disorder (kidney disease)
Cutaneous vasculitis (an inflammatory process affecting the vessel wall that leads to its damage)
Nasopharyngitis (inflammation of the nasopharynx)

What are the common drug interactions of Diflucan and Apixaban, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Crying
Depression
Emotional distress
Pain
Renal atrophy (wasting of kidney)
Renal impairment (severely reduced kidney function)
Restlessness (not able to rest)

30-39:

n/a

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress
Pain
Renal failure (kidney dysfunction)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Renal injury (kidney injury)

50-59:

Anxiety
Constipation
Cytomegalovirus test positive
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspnoea (difficult or laboured respiration)
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
Fatigue (feeling of tiredness)
Hypercholesterolaemia (high levels of cholesterol in the blood)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)

60+:

Pneumonia
Cardiac failure
Listless (lack of interest, energy, or spirit)
Lower respiratory tract infection
Pain
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Renal failure (kidney dysfunction)
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)

What are the existing conditions these people have? *

Pain: 7 people, 29.17%
Nausea (feeling of having an urge to vomit): 6 people, 25.00%
Nausea And Vomiting: 5 people, 20.83%
Stress And Anxiety: 5 people, 20.83%
Pulmonary Embolism (blockage of the main artery of the lung): 5 people, 20.83%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 16.67%
High Blood Pressure: 4 people, 16.67%
Hiv Infection: 4 people, 16.67%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 12.50%
High Blood Cholesterol: 3 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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