Daklinza and Zoloft drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Daklinza (daclatasvir dihydrochloride) and Zoloft (sertraline hydrochloride). Common drug interactions include death among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Daklinza and Zoloft. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Daklinza?

Daklinza has active ingredients of daclatasvir dihydrochloride. eHealthMe is studying from 3,312 Daklinza users. Check the latest studies of Daklinza.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,798 Zoloft users. Check the latest studies of Zoloft.

On Aug, 13, 2026

17 people who take Daklinza and Zoloft together, and have interactions are studied.

What are the common drug interactions of Daklinza and Zoloft, by gender? *:

female:

Death
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Pain
Pain in extremity
Pruritus (severe itching of the skin)
Rash
Retroperitoneal abscess (a collection of pus between the peritoneum and the posterior abdominal wall. retroperitoneal. behind the peritoneum)
Sepsis (a severe blood infection that can lead to organ failure and death)

male:

Fatigue (feeling of tiredness)
Pneumonia
Death
Dehydration (dryness resulting from the removal of water)
Hepatitis c
Hypertension (high blood pressure)
Hypoaesthesia (reduced sense of touch or sensation)
Lactic acidosis (low ph in body tissues)
Loss of consciousness
Memory impairment

What are the common drug interactions of Daklinza and Zoloft, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Headache (pain in head)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Pain
Pain in extremity
Pruritus (severe itching of the skin)
Rash

30-39:

Asthenia (weakness)
Death
Fatigue (feeling of tiredness)
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Loss of consciousness
Memory impairment
Migraine (headache)
Visual impairment

40-49:

Hepatitis c
Pneumonia
Abdominal distension
Abdominal pain lower
Psychotic disorder
Fatigue (feeling of tiredness)

50-59:

Death
Retroperitoneal abscess (a collection of pus between the peritoneum and the posterior abdominal wall. retroperitoneal. behind the peritoneum)
Sepsis (a severe blood infection that can lead to organ failure and death)
Fatigue (feeling of tiredness)
Lactic acidosis (low ph in body tissues)

60+:

n/a

What are the existing conditions these people have? *

Hepatitis C: 12 people, 70.59%
Stress And Anxiety: 1 person, 5.88%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 5.88%
Seasonal Allergy (allergic condition due to certain season): 1 person, 5.88%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 1 person, 5.88%
Insomnia (sleeplessness): 1 person, 5.88%
Diabetes: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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