Danazol and Zantac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Danazol (danazol) and Zantac (ranitidine hydrochloride). Common drug interactions include dyspnoea among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Danazol and Zantac. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Danazol?

Danazol has active ingredients of danazol. It is often used in hereditary angioedema. eHealthMe is studying from 3,716 Danazol users. Check the latest studies of Danazol.

What is Zantac?

Zantac has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 434,161 Zantac users. Check the latest studies of Zantac.

On Jul, 23, 2026

58 people who take Danazol and Zantac together, and have interactions are studied.

What are the common drug interactions of Danazol and Zantac, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)
Influenza
Injection site extravasation (flow of (blood or lymph) from injection site)
Liver disorder (liver diseases)
Neutropenia (an abnormally low number of neutrophils)
Oedema (fluid collection in tissue)
Platelet count decreased
Sepsis (a severe blood infection that can lead to organ failure and death)
Skin burning sensation

male:

Death
Drug ineffective
Decreased immune responsiveness
Dyspnoea (difficult or laboured respiration)
Ear haemorrhage (bleeding from ear)
Gamma-glutamyltransferase increased
Gingivitis (inflammation of gums)
Hepatitis (inflammation of the liver)
Hypersensitivity
Laceration (tearing of soft body tissue)

What are the common drug interactions of Danazol and Zantac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Liver disorder (liver diseases)
White blood cell count increased
Abortion spontaneous (naturally occurring miscarriage)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Embolism venous (embolus may pass into the arterial system)
Infertility female
Platelet count decreased
Scleroderma (hard skin)
Therapeutic response decreased (less preventive response)

30-39:

Abdominal distension
Asthma
Peripheral swelling

40-49:

Hemiparesis (weakness on one side of the body)
Immune thrombocytopenic purpura (destruction of blood platelets due to the presence of antiplatelet auto antibodies)
Migraine (headache)
Panic attack
Platelet count decreased
Pruritus generalised (generalized itching)
Subdural haematoma (blood collects between the skull and the surface of the brain)
Tearfulness (excess tearing)
Throat irritation
Thrombocytopenia (decrease of platelets in blood)

50-59:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Weight decreased
Abdominal pain
Acne (skin problems that cause pimples)
Alopecia (absence of hair from areas of the body)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Blood glucose decreased
Blood glucose increased
Breast discharge
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

60+:

Headache (pain in head)
Injection site swelling
Parotid gland enlargement
Pleural effusion (water on the lungs)
Syncope (loss of consciousness with an inability to maintain postural tone)
Breast cancer
Injection site extravasation (flow of (blood or lymph) from injection site)
Therapeutic response decreased (less preventive response)
Drug ineffective
Injection site discharge

What are the existing conditions these people have? *

Immune System Disorder: 12 people, 20.69%
Hypersensitivity: 7 people, 12.07%
Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 6 people, 10.34%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 6 people, 10.34%
Itching: 6 people, 10.34%
High Blood Pressure: 5 people, 8.62%
Asthma: 4 people, 6.90%
Depression: 4 people, 6.90%
Stress And Anxiety: 4 people, 6.90%
Nausea (feeling of having an urge to vomit): 4 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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