Dandelion and Methotrexate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dandelion (dandelion) and Methotrexate (methotrexate sodium). Common drug interactions include headache among females and cholelithiasis among males.

The phase IV clinical study analyzes what interactions people have when they take Dandelion and Methotrexate. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Dandelion?

Dandelion has active ingredients of dandelion. eHealthMe is studying from 272 Dandelion users. Check the latest studies of Dandelion.

What is Methotrexate?

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. eHealthMe is studying from 604,314 Methotrexate users. Check the latest studies of Methotrexate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

20 people who take Dandelion and Methotrexate together, and have interactions are studied.

Dandelion and Methotrexate drug interactions.

What are the common drug interactions of Dandelion and Methotrexate, by gender? *:

female:

Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Blood pressure increased
Arthralgia (joint pain)
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Benign neoplasm of thyroid gland (benign (non-cancerous) tumours of the thyroid gland)
Blood pressure systolic increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Drug intolerance (drug sensitivity)
Drug tolerance decreased

male:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Chest pain
Syncope (loss of consciousness with an inability to maintain postural tone)
Cholecystitis (infection of gallbladder)
Blood pressure increased
Chest discomfort
Dizziness
Dyspnoea (difficult or laboured respiration)
Fall
Hypoxia (low oxygen in tissues)

What are the common drug interactions of Dandelion and Methotrexate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Benign neoplasm of thyroid gland (benign (non-cancerous) tumours of the thyroid gland)
Blood pressure increased
Blood pressure systolic increased
Headache (pain in head)
Heart rate decreased
Infusion related reaction
Localised infection (infection at the single location)
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)
Oropharyngeal pain

50-59:

Headache (pain in head)
Arthralgia (joint pain)
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Drug intolerance (drug sensitivity)
Drug tolerance decreased
Foot deformity (functional disability of foot)
Hand deformity
Immune system disorder
Joint swelling

60+:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Blood pressure increased
Chest discomfort
Drug hypersensitivity
Erythema (redness of the skin)
Insomnia (sleeplessness)
Pruritus (severe itching of the skin)
Skin disorder (skin disease)
Chest pain
Cholecystitis (infection of gallbladder)

What are the existing conditions these people have? *

Hypersensitivity: 7 people, 35.00%
The Flu (the flu is caused by an influenza virus): 1 person, 5.00%
Stress And Anxiety: 1 person, 5.00%
Stable Angina (a constant chest pain): 1 person, 5.00%
Sinusitis (inflammation of sinus): 1 person, 5.00%
Rickets (softening of bones): 1 person, 5.00%
Pain: 1 person, 5.00%
Iron Deficiency: 1 person, 5.00%
Insomnia (sleeplessness): 1 person, 5.00%
Inflammation: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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