Daptomycin and Captopril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Daptomycin (daptomycin) and Captopril (captopril). Common drug interactions include acute interstitial pneumonitis among females and septic shock among males.

The phase IV clinical study analyzes what interactions people have when they take Daptomycin and Captopril. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Daptomycin?

Daptomycin has active ingredients of daptomycin. eHealthMe is studying from 7,879 Daptomycin users. Check the latest studies of Daptomycin.

What is Captopril?

Captopril has active ingredients of captopril. It is often used in high blood pressure. eHealthMe is studying from 17,438 Captopril users. Check the latest studies of Captopril.



On Jul, 26, 2026

37 people who take Daptomycin and Captopril together, and have interactions are studied.

Daptomycin and Captopril drug interactions.

What are the common drug interactions of Daptomycin and Captopril, by gender? *:

female:

  1. Acute interstitial pneumonitis (acute revere lung disease)
  2. Eosinophilia (eosinophil count in the peripheral blood exceeds)
  3. Delirium (wild excitement)
  4. Acute respiratory failure
  5. Adenocarcinoma pancreas (cancer of pancreas)
  6. Blood creatine increased
  7. Depression
  8. Jaundice cholestatic
  9. Metastases to liver (cancer spreads to liver)
  10. Microangiopathy (disease of the capillaries (very small blood vessels), in which the capillary walls become so thick and weak that they bleed, leak protein)

male:

  1. Septic shock (shock due to blood infection)
  2. Arrhythmia (irregular heartbeat)
  3. Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
  4. Hepatic failure (liver failure)
  5. Liver disorder (liver diseases)
  6. Pulmonary hypertension (increase in blood pressure in the lung artery)
  7. Renal failure acute (rapid kidney dysfunction)
  8. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  9. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  10. Pneumonia

What are the common drug interactions of Daptomycin and Captopril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Blood creatine increased

10-19:

  1. Acute respiratory failure
  2. Microangiopathy (disease of the capillaries (very small blood vessels), in which the capillary walls become so thick and weak that they bleed, leak protein)
  3. Pulmonary hypertension (increase in blood pressure in the lung artery)
  4. Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)

20-29:

n/a

30-39:

n/a

40-49:

  1. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
  2. Haemorrhage intracranial (bleeding within the skull)
  3. Hypotension (abnormally low blood pressure)
  4. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  5. Poisoning
  6. Respiratory failure (inadequate gas exchange by the respiratory system)
  7. Sepsis (a severe blood infection that can lead to organ failure and death)

50-59:

  1. Septic shock (shock due to blood infection)
  2. Arrhythmia (irregular heartbeat)
  3. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  4. Cardiac failure congestive
  5. Cardiac output decreased
  6. Cardiogenic shock (inadequate circulation of blood)
  7. Cerebellar ischaemia (lack of blood supply to cerebeller)
  8. Encephalopathy (functioning of the brain is affected by some agent or condition)
  9. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  10. Haematoma (collection of blood outside the blood vessels)

60+:

  1. Acute interstitial pneumonitis (acute revere lung disease)
  2. Eosinophilia (eosinophil count in the peripheral blood exceeds)
  3. Pancreatic carcinoma metastatic (pancreatic cancer- metastatic)
  4. Delirium (wild excitement)
  5. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  6. Adenocarcinoma pancreas (cancer of pancreas)
  7. Depression
  8. Jaundice cholestatic
  9. Metastases to liver (cancer spreads to liver)
  10. Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)

What are the existing conditions these people have? *

  1. Urinary Tract Infection: 18 people, 48.65%
  2. Postoperative Wound Infection: 13 people, 35.14%
  3. Enlarged Prostate: 5 people, 13.51%
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 10.81%
  5. Hyperglycemia (high blood sugar): 3 people, 8.11%
  6. High Blood Cholesterol: 3 people, 8.11%
  7. Pain: 3 people, 8.11%
  8. Diabetic Ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 3 people, 8.11%
  9. Immunodeficiency Disorders: 3 people, 8.11%
  10. Fever: 3 people, 8.11%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Daptomycin and Captopril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Daptomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Captopril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Daptomycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Captopril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on daptomycin and captopril (the active ingredients of Daptomycin and Captopril, respectively), and Daptomycin and Captopril (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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