Daptomycin and Mupirocin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Daptomycin (daptomycin) and Mupirocin (mupirocin). Common drug interactions include sinusitis among females and enterocutaneous fistula among males.

The phase IV clinical study analyzes what interactions people have when they take Daptomycin and Mupirocin. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Daptomycin?

Daptomycin has active ingredients of daptomycin. eHealthMe is studying from 7,879 Daptomycin users. Check the latest studies of Daptomycin.

What is Mupirocin?

Mupirocin has active ingredients of mupirocin. It is often used in impetigo. eHealthMe is studying from 5,940 Mupirocin users. Check the latest studies of Mupirocin.



On Aug, 04, 2026

26 people who take Daptomycin and Mupirocin together, and have interactions are studied.

Daptomycin and Mupirocin drug interactions.

What are the common drug interactions of Daptomycin and Mupirocin, by gender? *:

female:

  1. Sinusitis (inflammation of sinus)
  2. Oxygen saturation decreased
  3. Chills (felling of cold)
  4. Electrolyte imbalance
  5. Headache (pain in head)
  6. Humerus fracture (injury to the upper arm bone)
  7. Infusion site extravasation (flow of (blood or lymph) from infusion site)
  8. Joint swelling
  9. Oedema (fluid collection in tissue)
  10. Rash

male:

  1. Enterocutaneous fistula
  2. Hypotension (abnormally low blood pressure)
  3. Dehydration (dryness resulting from the removal of water)
  4. General physical health deterioration (weak health status)
  5. Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
  6. Dementia (madness)
  7. Hypertension (high blood pressure)
  8. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  9. Loss of consciousness
  10. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)

What are the common drug interactions of Daptomycin and Mupirocin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Respiratory distress (difficulty in breathing)
  2. Acute respiratory failure
  3. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
  4. Herpes simplex ophthalmic (eye infection is caused by a type of herpes simplex virus)
  5. Pneumonia
  6. Pneumonia fungal
  7. Pneumonia viral
  8. Pulmonary haemorrhage (acute bleeding from the lung)
  9. Pulmonary oedema (fluid accumulation in the lungs)
  10. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)

30-39:

  1. Sepsis (a severe blood infection that can lead to organ failure and death)
  2. Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
  3. Anal abscess
  4. Catheter sepsis (bacterial infection in blood due to catheter)
  5. Cellulitis (infection under the skin)
  6. Confusional state
  7. Diarrhoea
  8. Enterococcal infection
  9. General physical health deterioration (weak health status)
  10. Genital abscess (build up of pus in genital)

40-49:

  1. Enterocutaneous fistula

50-59:

  1. Cardiac arrest
  2. Dehydration (dryness resulting from the removal of water)
  3. Bacteraemia (presence of bacteria in the blood)
  4. Oxygen saturation decreased
  5. Blood potassium increased
  6. Chills (felling of cold)
  7. Headache (pain in head)
  8. Infusion site extravasation (flow of (blood or lymph) from infusion site)
  9. Joint swelling
  10. Klebsiella infection

60+:

  1. Hypotension (abnormally low blood pressure)
  2. Respiratory failure (inadequate gas exchange by the respiratory system)
  3. Nausea (feeling of having an urge to vomit)
  4. Pneumonia
  5. Renal failure acute (rapid kidney dysfunction)
  6. Renal failure chronic (long lasting kidney dysfunction)
  7. Sepsis (a severe blood infection that can lead to organ failure and death)
  8. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
  9. Subdural haematoma (blood collects between the skull and the surface of the brain)
  10. Thrombocytopenia (decrease of platelets in blood)

What are the existing conditions these people have? *

  1. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 8 people, 30.77%
  2. Sepsis (a severe blood infection that can lead to organ failure and death): 7 people, 26.92%
  3. Itching: 7 people, 26.92%
  4. Post Procedural Complication: 6 people, 23.08%
  5. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 15.38%
  6. Infection: 2 people, 7.69%
  7. Hypotension (abnormally low blood pressure): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Daptomycin and Mupirocin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Daptomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Mupirocin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Daptomycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mupirocin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on daptomycin and mupirocin (the active ingredients of Daptomycin and Mupirocin, respectively), and Daptomycin and Mupirocin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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