Daptomycin and Zopiclone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Daptomycin (daptomycin) and Zopiclone (eszopiclone). Common drug interactions include neutropenia among females and enterobacter pneumonia among males.
The phase IV clinical study analyzes what interactions people have when they take Daptomycin and Zopiclone. It is created by eHealthMe based on reports of 90 people who take the same drugs from the FDA, and is updated regularly.
What is Daptomycin?
Daptomycin has active ingredients of daptomycin. eHealthMe is studying from 7,879 Daptomycin users. Check the latest studies of Daptomycin.
What is Zopiclone?
Zopiclone has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 54,330 Zopiclone users. Check the latest studies of Zopiclone.
90 people who take Daptomycin and Zopiclone together, and have interactions are studied.

What are the common drug interactions of Daptomycin and Zopiclone, by gender? *:
female:
- Neutropenia (an abnormally low number of neutrophils)
- Pyrexia (fever)
- Liver disorder (liver diseases)
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
- Abdominal pain
- Campylobacter infection (infection by the campylobacter bacterium)
- Cholecystitis (infection of gallbladder)
- Gastrointestinal infection (infection of stomach and intestine)
- General physical condition
- Hypokalaemia (low potassium)
male:
- Enterobacter pneumonia (lung inflammation caused by bacteria of the family enterobacteriaceae)
- Escherichia infection (bacterial infection by escherichia coli)
- Liver abscess (pus in liver)
- Pneumonia
- Vasculitis (inflammation of a blood vessel or blood vessels)
- Enterobacter sepsis (sepsis due to bacteria of the family enterobacteriaceae)
- Vasculitis necrotising (inflammation and damage to blood vessels)
- Diarrhoea
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Endocarditis (inflammation in heart muscle)
What are the common drug interactions of Daptomycin and Zopiclone, by age (0-1 to 60+)? *:
0-1:
- Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
- Enterobacter pneumonia (lung inflammation caused by bacteria of the family enterobacteriaceae)
- Escherichia infection (bacterial infection by escherichia coli)
- Staphylococcal infection (an infection with staphylococcus bacteria)
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Abdominal pain
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Atrioventricular block complete (heart block complete)
- Bleeding time prolonged
- Chest pain
- Dyspnoea (difficult or laboured respiration)
- Endocarditis (inflammation in heart muscle)
- Hyperhidrosis (abnormally increased sweating)
- Nausea (feeling of having an urge to vomit)
- Pain
40-49:
n/a
50-59:
- Anaemia (lack of blood)
- Oedema (fluid collection in tissue)
- Systemic candida (whole body fungal infection)
- Respiratory gas exchange disorder (gas exchange disease of respiratory system)
- Renal failure (kidney dysfunction)
- Hypercapnia (too much smoke)
- Liver abscess (pus in liver)
- Vasculitis (inflammation of a blood vessel or blood vessels)
- Enterobacter sepsis (sepsis due to bacteria of the family enterobacteriaceae)
- Encephalopathy (functioning of the brain is affected by some agent or condition)
60+:
- Enterobacter pneumonia (lung inflammation caused by bacteria of the family enterobacteriaceae)
- Escherichia infection (bacterial infection by escherichia coli)
- Diarrhoea
- Lung disorder (lung disease)
- Abdominal pain
- Campylobacter infection (infection by the campylobacter bacterium)
- Cholecystitis (infection of gallbladder)
- Gastrointestinal infection (infection of stomach and intestine)
- General physical condition
- Hypokalaemia (low potassium)
What are the existing conditions these people have? *
- High Blood Pressure: 22 people, 24.44%
- Pyogenic Liver Abscess (liver abscess caused by bacteria): 21 people, 23.33%
- Hypokalemia (low potassium): 20 people, 22.22%
- Peritoneal Disorder: 19 people, 21.11%
- Constipation: 15 people, 16.67%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 14 people, 15.56%
- Arrhythmias (irregular heartbeat): 14 people, 15.56%
- Sleep Disorder: 14 people, 15.56%
- Hyperuricaemia (level of uric acid in the blood that is abnormally high): 14 people, 15.56%
- Infection: 14 people, 15.56%
* Approximation only. Some reports may have incomplete information.
Do you take Daptomycin and Zopiclone?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Daptomycin (7,879 reports)
- Zopiclone (54,330 reports)
Browse all drug interactions of Daptomycin and Zopiclone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Daptomycin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zopiclone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Daptomycin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zopiclone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .
- Saliho?lu M, Turhan V, ?nem Y, Ulcay A, Uzun G, Ay H, "Sudden hearing loss in a patient receiving piperacillin/tazobactam and daptomycin for diabetic foot infection", Scandinavian journal of infectious diseases, 2013 Mar .
- Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .
- Saliho?lu M, Turhan V, ?nem Y, Ulcay A, Uzun G, Ay H, "Sudden hearing loss in a patient receiving piperacillin/tazobactam and daptomycin for diabetic foot infection", Scandinavian journal of infectious diseases, 2013 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on daptomycin and eszopiclone (the active ingredients of Daptomycin and Zopiclone, respectively), and Daptomycin and Zopiclone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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