Darvocet-n 100 and Macrodantin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Darvocet-n 100 (acetaminophen; propoxyphene napsylate) and Macrodantin (nitrofurantoin, macrocrystalline). Common drug interactions include drug hypersensitivity among females.

The phase IV clinical study analyzes what interactions people have when they take Darvocet-n 100 and Macrodantin. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Darvocet-n 100?

Darvocet-n 100 has active ingredients of acetaminophen; propoxyphene napsylate. It is often used in pain. eHealthMe is studying from 2,893 Darvocet-n 100 users. Check the latest studies of Darvocet-n 100.

What is Macrodantin?

Macrodantin has active ingredients of nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 3,755 Macrodantin users. Check the latest studies of Macrodantin.

On Jul, 15, 2026

17 people who take Darvocet-n 100 and Macrodantin together, and have interactions are studied.

Darvocet-n 100 and Macrodantin drug interactions.

What are the common drug interactions of Darvocet-N 100 and Macrodantin, by gender? *:

female:

Drug hypersensitivity
Nausea (feeling of having an urge to vomit)
Fall
Hypoaesthesia (reduced sense of touch or sensation)
International normalised ratio decreased
International normalised ratio increased
Neutropenia (an abnormally low number of neutrophils)
Periorbital haematoma (collection of blood around the eyes)
Pulmonary embolism (blockage of the main artery of the lung)
Pyrexia (fever)

male:

n/a

What are the common drug interactions of Darvocet-N 100 and Macrodantin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Drug hypersensitivity
Insomnia (sleeplessness)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Urticaria (rash of round, red welts on the skin that itch intensely)

50-59:

Cardiac failure
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest pain
Weight fluctuation
Blood cholesterol increased
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Difficulty in walking
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)

60+:

Drug hypersensitivity
Abasia (inability to walk)
Nausea (feeling of having an urge to vomit)
Neutropenia (an abnormally low number of neutrophils)
Pain in extremity
Periorbital haematoma (collection of blood around the eyes)
Pulmonary embolism (blockage of the main artery of the lung)
Pyrexia (fever)
Scar
Skin discolouration (change of skin colour)

What are the existing conditions these people have? *

Type 2 Diabetes: 2 people, 11.76%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 11.76%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 2 people, 11.76%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.88%
Osteoporosis (bones weak and more likely to break): 1 person, 5.88%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 1 person, 5.88%
Colon Cancer Metastatic (cancer of colon spreads to other part of body): 1 person, 5.88%
Breast Cancer Female: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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