Darvocet and Seroquel xr drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Darvocet (acetaminophen; propoxyphene hydrochloride) and Seroquel xr (quetiapine fumarate). Common drug interactions include chronic obstructive pulmonary disease among females and abdominal symptom among males.

The phase IV clinical study analyzes what interactions people have when they take Darvocet and Seroquel xr. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Darvocet?

Darvocet has active ingredients of acetaminophen; propoxyphene hydrochloride. It is often used in pain. eHealthMe is studying from 12,131 Darvocet users. Check the latest studies of Darvocet.

What is Seroquel xr?

Seroquel xr has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 11,825 Seroquel xr users. Check the latest studies of Seroquel xr.



On Jul, 09, 2026

11 people who take Darvocet and Seroquel xr together, and have interactions are studied.

Darvocet and Seroquel xr drug interactions.

What are the common drug interactions of Darvocet and Seroquel Xr, by gender? *:

female:

  1. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  2. Depression
  3. Frustration (a form of poorly expressed anger)
  4. Nasopharyngitis (inflammation of the nasopharynx)
  5. Non-cardiac chest pain
  6. Panic attack
  7. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  8. Respiratory disorder (respiratory disease)
  9. Tremor (trembling or shaking movements in one or more parts of your body)
  10. Vitamin d deficiency

male:

  1. Abdominal symptom
  2. Abscess jaw (tooth abscess or root abscess)
  3. Ascites (accumulation of fluid in the abdominal cavity)
  4. Asthenia (weakness)
  5. Atelectasis (partial or complete collapse of the lung)
  6. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  7. Atrioventricular block (heart block)
  8. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  9. Bacteraemia (presence of bacteria in the blood)
  10. Benign prostatic hyperplasia (benign enlargement of the prostate)

What are the common drug interactions of Darvocet and Seroquel Xr, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Abnormal behaviour
  2. Aggression
  3. Hostility
  4. Pain in extremity

30-39:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)

40-49:

n/a

50-59:

  1. Insomnia (sleeplessness)
  2. Post-traumatic stress disorder
  3. Restless legs syndrome (a powerful urge to move your legs)
  4. Anxiety
  5. Blood cholesterol increased
  6. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  7. Frustration (a form of poorly expressed anger)
  8. Nasopharyngitis (inflammation of the nasopharynx)
  9. Non-cardiac chest pain
  10. Panic attack

60+:

  1. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  2. Depression
  3. Insomnia (sleeplessness)
  4. Nightmare (unpleasant dream)
  5. Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
  6. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  7. Joint swelling
  8. Mania (a state of abnormally elevated or irritable mood)
  9. Oedema peripheral (superficial swelling)
  10. Psychotic disorder

What are the existing conditions these people have? *

  1. Depression: 4 people, 36.36%
  2. High Blood Cholesterol: 2 people, 18.18%
  3. Insomnia (sleeplessness): 2 people, 18.18%
  4. Stress And Anxiety: 2 people, 18.18%
  5. Tremor (trembling or shaking movements in one or more parts of your body): 1 person, 9.09%
  6. High Blood Pressure: 1 person, 9.09%
  7. Bipolar Ii Disorder (characterized by at least one episode of hypomania and at least one episode of major depression): 1 person, 9.09%
  8. Blood Testosterone Decreased: 1 person, 9.09%
  9. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 9.09%
  10. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Darvocet and Seroquel xr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Darvocet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Seroquel xr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Darvocet and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Seroquel xr and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; propoxyphene hydrochloride and quetiapine fumarate (the active ingredients of Darvocet and Seroquel xr, respectively), and Darvocet and Seroquel xr (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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