Diabeta and Effexor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diabeta (glyburide) and Effexor (venlafaxine hydrochloride). Common drug interactions include disseminated intravascular coagulation among females and arrhythmia among males.

The phase IV clinical study analyzes what interactions people have when they take Diabeta and Effexor. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Diabeta?

Diabeta has active ingredients of glyburide. It is often used in type 2 diabetes. eHealthMe is studying from 3,119 Diabeta users. Check the latest studies of Diabeta.

What is Effexor?

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,493 Effexor users. Check the latest studies of Effexor.



On Jul, 09, 2026

31 people who take Diabeta and Effexor together, and have interactions are studied.

Diabeta and Effexor drug interactions.

What are the common drug interactions of Diabeta and Effexor, by gender? *:

female:

  1. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  2. Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
  3. Drug dependence
  4. Dry mouth
  5. Dysphagia (a condition in which swallowing is difficult or painful)
  6. Dyspnoea (difficult or laboured respiration)
  7. Dysuria (painful or difficult urination)
  8. Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
  9. Essential hypertension (primary hypertension)
  10. Feeling drunk

male:

  1. Arrhythmia (irregular heartbeat)
  2. Cardiac disorder
  3. Confusional state
  4. Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
  5. Death
  6. Dehydration (dryness resulting from the removal of water)
  7. Depressed mood
  8. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  9. Headache (pain in head)
  10. Hyperglycaemia (high blood sugar)

What are the common drug interactions of Diabeta and Effexor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal pain lower
  2. Agitation (state of anxiety or nervous excitement)
  3. Blood cholesterol increased
  4. Blood triglycerides increased
  5. Cardiac failure congestive
  6. Diarrhoea
  7. Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
  8. Drug dependence
  9. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  10. Dry mouth

50-59:

  1. Micturition disorder (disease of passing urine)
  2. Mobility decreased (ability to move is reduced)
  3. Muscle spasms (muscle contraction)
  4. Nasopharyngitis (inflammation of the nasopharynx)
  5. Pain in extremity
  6. Polyuria (production of too much dilute urine)
  7. Skin discolouration (change of skin colour)
  8. Urinary tract infection
  9. Weight decreased
  10. Wound

60+:

  1. Arrhythmia (irregular heartbeat)
  2. Cardiac disorder
  3. Pericardial effusion (fluid around the heart)
  4. Abdominal distension
  5. Abdominal pain
  6. Acute sinusitis
  7. Alanine aminotransferase increased
  8. Alcoholism (problems with alcohol)
  9. Anaemia (lack of blood)
  10. Aortic valve incompetence

What are the existing conditions these people have? *

  1. Stress And Anxiety: 5 people, 16.13%
  2. Pain: 4 people, 12.90%
  3. Diabetes: 4 people, 12.90%
  4. Nausea (feeling of having an urge to vomit): 3 people, 9.68%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 9.68%
  6. Sinus Congestion (blockage of sinus): 2 people, 6.45%
  7. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Diabeta and Effexor?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Diabeta and Effexor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Diabeta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Effexor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Diabeta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Effexor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on glyburide and venlafaxine hydrochloride (the active ingredients of Diabeta and Effexor, respectively), and Diabeta and Effexor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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