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Geodon and Senna drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Geodon (ziprasidone hydrochloride) and Senna (senna). Common drug interactions include type 2 diabetes mellitus among females and bradycardia among males.

The phase IV clinical study analyzes what interactions people have when they take Geodon and Senna. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Geodon?

Geodon has active ingredients of ziprasidone hydrochloride. It is often used in bipolar disorder. eHealthMe is studying from 19,504 Geodon users. Check the latest studies of Geodon.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

On Jul, 09, 2026

25 people who take Geodon and Senna together, and have interactions are studied.

Geodon and Senna drug interactions.

What are the common drug interactions of Geodon and Senna, by gender? *:

female:

  1. Type 2 diabetes mellitus
  2. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  3. Blood glucose increased
  4. Diabetes mellitus inadequate control
  5. Gastrointestinal injury (injury to gastrointestinal tract)
  6. Hyperglycaemia (high blood sugar)
  7. Intracardiac thrombus (presence of a circumscribed mass with heart wall)
  8. Pneumonia
  9. Pulmonary embolism (blockage of the main artery of the lung)
  10. Type 1 diabetes mellitus

male:

  1. Bradycardia (abnormally slow heart action)
  2. Hypertension (high blood pressure)
  3. Fall
  4. Fatigue (feeling of tiredness)
  5. Gait disturbance
  6. Gastric dilatation (a twisted stomach)
  7. Gastric ulcer perforation (stomach hole due to ulcer)
  8. Implant site erosion
  9. Intentional self-injury
  10. Lethargy (tiredness)

What are the common drug interactions of Geodon and Senna, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Abnormal behaviour

20-29:

  1. Gastrointestinal injury (injury to gastrointestinal tract)
  2. Intracardiac thrombus (presence of a circumscribed mass with heart wall)
  3. Pulmonary embolism (blockage of the main artery of the lung)

30-39:

  1. Blood glucose increased
  2. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  3. Diabetes mellitus inadequate control
  4. Hyperglycaemia (high blood sugar)
  5. Type 1 diabetes mellitus
  6. Type 2 diabetes mellitus
  7. Vision blurred
  8. Bradycardia (abnormally slow heart action)
  9. Hypertension (high blood pressure)
  10. Implant site erosion

40-49:

  1. Type 2 diabetes mellitus
  2. Abdominal pain
  3. Adverse drug reaction
  4. Agitation (state of anxiety or nervous excitement)
  5. Anxiety
  6. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  7. Cerebrovascular disorder (disease of brain)
  8. Chest pain
  9. Chronic kidney disease
  10. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

50-59:

  1. Cardiac failure congestive
  2. Gastric ulcer perforation (stomach hole due to ulcer)
  3. Hallucination, auditory (perceiving sounds without auditory stimulus)
  4. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  5. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  6. Urinary tract infection

60+:

  1. Cardiac arrest
  2. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  3. Tremor (trembling or shaking movements in one or more parts of your body)
  4. Vomiting
  5. Confusional state
  6. Fatigue (feeling of tiredness)
  7. Gait disturbance
  8. Gastric dilatation (a twisted stomach)
  9. Lethargy (tiredness)
  10. Localised infection (infection at the single location)

What are the existing conditions these people have? *

  1. Pain: 5 people, 20.00%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 16.00%
  3. Depression: 4 people, 16.00%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 12.00%
  5. Insomnia (sleeplessness): 3 people, 12.00%
  6. Stress And Anxiety: 2 people, 8.00%
  7. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 2 people, 8.00%
  8. Quit Smoking: 2 people, 8.00%
  9. Nausea (feeling of having an urge to vomit): 2 people, 8.00%
  10. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Geodon and Senna?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Geodon and Senna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Geodon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Senna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Geodon and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Senna and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ziprasidone hydrochloride and senna (the active ingredients of Geodon and Senna, respectively), and Geodon and Senna (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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