Suboxone and Mouth ulceration aggravated - a phase IV clinical study of FDA data

Summary:

Mouth ulceration aggravated is reported as a side effect among people who take Suboxone (buprenorphine hydrochloride; naloxone hydrochloride), especially for people who are female, 30-39 old, have been taking the drug for 1 - 6 months also take Lidoderm, and have Drug dependence.

The phase IV clinical study analyzes which people have Mouth ulceration aggravated when taking Suboxone. It is created by eHealthMe based on reports of 28,308 people who have side effects when taking Suboxone from the FDA, and is updated regularly.

What is Suboxone?

Suboxone has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. It is often used in opiate withdrawal. eHealthMe is studying from 31,249 Suboxone users. Check the latest studies of Suboxone.

What is Mouth ulceration aggravated?

Mouth ulceration aggravated (mouth ulcers) is found to be associated with 1,059 drugs and 360 conditions by eHealthMe. Check the latest studies of Mouth ulceration aggravated.

On Jul, 09, 2026

28,308 people reported to have side effects when taking Suboxone.
Among them, 55 people (0.19%) have Mouth ulceration aggravated.

Could Suboxone cause Mouth ulceration aggravated?

Among these 55 people:

How long have people been on Suboxone when they have Mouth ulceration aggravated? *

What is the gender of people who have Mouth ulceration aggravated when taking Suboxone? *

female: 65.96 %
male: 34.04 %

What is the age of people who have Mouth ulceration aggravated when taking Suboxone? *

What are other drugs people take besides Suboxone? *

What are other side effects people have besides Mouth ulceration aggravated? *

Oral Pain: 8 people, 14.55%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 9.09%
Nausea (feeling of having an urge to vomit): 5 people, 9.09%
Malaise (a feeling of general discomfort or uneasiness): 5 people, 9.09%
Tongue Ulceration (ulcers on tongue): 5 people, 9.09%
Stomatitis (inflammation of mucous membrane of mouth): 4 people, 7.27%
Lactic Acidosis (low ph in body tissues): 4 people, 7.27%
Diabetes: 4 people, 7.27%
Swollen Tongue (swelling of tongue): 4 people, 7.27%
Drug Ineffective: 3 people, 5.45%

What are the existing conditions these people have? *

Drug Dependence: 25 people, 45.45%
Wheezing (a high-pitched whistling sound made while you breath): 4 people, 7.27%
Diabetes: 4 people, 7.27%
Pain: 4 people, 7.27%
Nausea And Vomiting: 4 people, 7.27%
Nausea (feeling of having an urge to vomit): 4 people, 7.27%
Urinary Tract Disorder: 4 people, 7.27%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 7.27%
Joint Pain: 4 people, 7.27%
High Blood Cholesterol: 1 person, 1.82%

* Approximation only. Some reports may have incomplete information.

Do you take Suboxone and have Mouth ulceration aggravated?

- Check whether Mouth ulceration aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Suboxone:

Suboxone (31,249 reports)

Mouth ulceration aggravated treatments and more:

Mouth ulceration aggravated (17 reports)

How severe was Mouth ulceration aggravated and when was it recovered:

Mouth ulceration aggravated in Suboxone

Expand to all the drugs that have ingredients of buprenorphine hydrochloride; naloxone hydrochloride:

Mouth ulceration aggravated and drugs with ingredients of buprenorphine hydrochloride; naloxone hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Suboxone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mouth ulceration aggravated:

Mouth ulceration aggravated (1,059 drugs)

Browse all the conditions that are associated with Mouth ulceration aggravated:

Mouth ulceration aggravated (360 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on buprenorphine hydrochloride; naloxone hydrochloride (the active ingredients of Suboxone) and Suboxone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.