Decadron and Opsumit drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Decadron (dexamethasone) and Opsumit (macitentan). Common drug interactions include dyspnoea among females.
The phase IV clinical study analyzes what interactions people have when they take Decadron and Opsumit. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Decadron?
Decadron has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 47,210 Decadron users. Check the latest studies of Decadron.
What is Opsumit?
Opsumit has active ingredients of macitentan. eHealthMe is studying from 67,926 Opsumit users. Check the latest studies of Opsumit.
11 people who take Decadron and Opsumit together, and have interactions are studied.

What are the common drug interactions of Decadron and Opsumit, by gender? *:
female:
- Dyspnoea (difficult or laboured respiration)
- Pyrexia (fever)
- Oedema (fluid collection in tissue)
- Pleural effusion (water on the lungs)
- Pneumonia
- Pulmonary hypertension (increase in blood pressure in the lung artery)
- Weight increased
- Autoimmune hepatitis
- Collagen disorder (infection and weakness of collagen)
- Diarrhoea
male:
n/a
What are the common drug interactions of Decadron and Opsumit, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Blister infected (infection of small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Blood culture positive
- Catheter site infection (infection at the site of insertion)
- Chills (felling of cold)
- Chronic respiratory failure
- Dyspnoea (difficult or laboured respiration)
- Fluid overload (too much fluid in the blood)
- Hyperhidrosis (abnormally increased sweating)
- Hypersensitivity
- Hypotension (abnormally low blood pressure)
30-39:
- Anxiety
- Cardiac arrest
- Cardiomegaly (increased size of heart than normal)
- Cough
- Depressed level of consciousness
- Dyspnoea (difficult or laboured respiration)
- Headache (pain in head)
- Insomnia (sleeplessness)
- Oedema (fluid collection in tissue)
- Pleural effusion (water on the lungs)
40-49:
n/a
50-59:
n/a
60+:
- Diarrhoea
- Anaemia (lack of blood)
- Brain neoplasm malignant (brain cancer tumour)
- Cardiac arrest
- Chemotherapy
- Dyspnoea (difficult or laboured respiration)
- Memory impairment
- Platelet count decreased
- Pyrexia (fever)
- Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
What are the existing conditions these people have? *
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 7 people, 63.64%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 54.55%
- Fever: 3 people, 27.27%
- Urinary Tract Infection: 2 people, 18.18%
- Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 2 people, 18.18%
- Cardiac Failure: 2 people, 18.18%
- Diarrhea: 2 people, 18.18%
- Gastric Cancer (stomach cancer): 2 people, 18.18%
- Hypocalcaemia (levels of calcium in blood serum are abnormally low): 2 people, 18.18%
- Cancer Pain: 2 people, 18.18%
* Approximation only. Some reports may have incomplete information.
Do you take Decadron and Opsumit?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Decadron and Opsumit:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Decadron:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Opsumit:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Decadron and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Opsumit and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Bartlett R, Hartle AJ, "Routine use of dexamethasone for postoperative nausea and vomiting: the case against", Anaesthesia, 2013 Sep .
- Bartlett R, Hartle AJ, "Routine use of dexamethasone for postoperative nausea and vomiting: the case against", Anaesthesia, 2013 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on dexamethasone and macitentan (the active ingredients of Decadron and Opsumit, respectively), and Decadron and Opsumit (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Effexor and Skelaxin drug interactions for women aged 50-59 - 6 seconds ago
- Lorazepam and Prilosec drug interactions for men aged 60+ - 7 seconds ago
- Ventolin and Seizure Disorder for Men aged 60+ - 28 seconds ago
- Ventolin and Epilepsy for Men aged 60+ - 28 seconds ago
- Could Lortab cause Pancreatic Disorder? - 29 seconds ago
- Nuvigil and Ibuprofen drug interactions for women aged 30-39 - 30 seconds ago
- Agitation in Paxil, how severe and when it was recovered? - 32 seconds ago
- Drug interactions of Cipro and Aripiprazole - 43 seconds ago
- Fenofibrate and Triamterene And Hydrochlorothiazide drug interactions for women aged 60+ - 45 seconds ago
- Bortezomib and High Blood Pressure for Women aged 50-59 - 59 seconds ago