Cipro and Aripiprazole drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cipro (ciprofloxacin hydrochloride) and Aripiprazole (aripiprazole). Common drug interactions include back pain among females and aggression among males.
The phase IV clinical study analyzes what interactions people have when they take Cipro and Aripiprazole. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.
What is Cipro?
Cipro has active ingredients of ciprofloxacin hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 35,126 Cipro users. Check the latest studies of Cipro.
What is Aripiprazole?
Aripiprazole has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 39,143 Aripiprazole users. Check the latest studies of Aripiprazole.
37 people who take Cipro and Aripiprazole together, and have interactions are studied.

What are the common drug interactions of Cipro and Aripiprazole, by gender? *:
female:
- Back pain
- Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Fatigue (feeling of tiredness)
- Hysterectomy
- Loss of consciousness
- Mania (a state of abnormally elevated or irritable mood)
- Suicidal ideation
- Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
- Vitamin d deficiency
male:
- Aggression
- Acute psychosis (period of mentally unstable behaviour)
- Dizziness
- Eyelid ptosis (falling of the upper or lower eyelid)
- Haematocrit decreased
- Haemoglobin decreased
- Hyperphagia (an abnormal appetite for food)
- Hypophagia (reduced food intake)
- Hypotension (abnormally low blood pressure)
- Polydipsia (excessive thirst)
What are the common drug interactions of Cipro and Aripiprazole, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Dyspnoea (difficult or laboured respiration)
- Loss of consciousness
- Painful respiration
30-39:
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hysterectomy
- Mania (a state of abnormally elevated or irritable mood)
- Neuropathy peripheral (surface nerve damage)
- Suicidal ideation
- Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
- Vitamin d deficiency
- Abdominal distension
- Abdominal pain upper
40-49:
- Chronic kidney disease
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Pneumonia
- Rash macular (small, flat red spots)
- Renal failure (kidney dysfunction)
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
- Skin induration (an abnormally hard spot or area on the skin)
- Sleep disorder
50-59:
- Fall
- Limb injury
- Mobility decreased (ability to move is reduced)
- Acute psychosis (period of mentally unstable behaviour)
- Arthralgia (joint pain)
- Abnormal behaviour
- Aggression
- Asterixis (flapping tremor, or liver flap)
- Chest pain
- Chronic kidney disease
60+:
- Haemoglobin decreased
- Abdominal pain upper
- Nasopharyngitis (inflammation of the nasopharynx)
- Nausea (feeling of having an urge to vomit)
- Pneumonia
- Pulmonary embolism (blockage of the main artery of the lung)
- Pulmonary mass
- Seasonal allergy (allergic condition due to certain season)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Aggression
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 16.22%
- Pain: 6 people, 16.22%
- High Blood Pressure: 6 people, 16.22%
- Infection: 5 people, 13.51%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 10.81%
- Cystic Fibrosis (disease of the secretary glands): 4 people, 10.81%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 10.81%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 10.81%
- Drowsiness: 4 people, 10.81%
- Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 8.11%
* Approximation only. Some reports may have incomplete information.
Do you take Cipro and Aripiprazole?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Cipro (35,126 reports)
- Aripiprazole (39,143 reports)
Browse all drug interactions of Cipro and Aripiprazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cipro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Aripiprazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cipro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Aripiprazole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Cetin, M., Celik, M., Cakici, M., Polat, M., & Suner, A, "Aripiprazole-Induced Hoarseness", Turk Psikiyatri Dergisi, 2018 Jan .
- Cetin M, Celik M, Cakici M, Polat M, Suner A, "Aripiprazole induced non-cardiogenic pulmonary edema: a case report", Turk Psikiyatri Dergisi, 2014 Dec .
- Cetin, M., Celik, M., Cakici, M., Polat, M., & Suner, A, "Aripiprazole-Induced Hoarseness", Turk Psikiyatri Dergisi, 2018 Jan .
- Cetin M, Celik M, Cakici M, Polat M, Suner A, "Aripiprazole induced non-cardiogenic pulmonary edema: a case report", Turk Psikiyatri Dergisi, 2014 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on ciprofloxacin hydrochloride and aripiprazole (the active ingredients of Cipro and Aripiprazole, respectively), and Cipro and Aripiprazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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