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Demerol and Amicar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Demerol (meperidine hydrochloride) and Amicar (aminocaproic acid). Common drug interactions include brain abscess among females and caecitis among males.

The phase IV clinical study analyzes what interactions people have when they take Demerol and Amicar. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Demerol?

Demerol has active ingredients of meperidine hydrochloride. It is often used in pain. eHealthMe is studying from 12,706 Demerol users. Check the latest studies of Demerol.

What is Amicar?

Amicar has active ingredients of aminocaproic acid. eHealthMe is studying from 1,323 Amicar users. Check the latest studies of Amicar.

On Jul, 29, 2026

15 people who take Demerol and Amicar together, and have interactions are studied.

Demerol and Amicar drug interactions.

What are the common drug interactions of Demerol and Amicar, by gender? *:

female:

  1. Brain abscess
  2. Injection site bruising
  3. Thrombosis (formation of a blood clot inside a blood vessel)

male:

  1. Caecitis (inflammation of the cecum)
  2. Escherichia infection (bacterial infection by escherichia coli)
  3. Fear
  4. Injury
  5. Multi-organ failure (multisystem organ failure)
  6. Renal failure (kidney dysfunction)
  7. Renal impairment (severely reduced kidney function)
  8. Renal injury (kidney injury)
  9. Stress
  10. Abdominal pain

What are the common drug interactions of Demerol and Amicar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Caecitis (inflammation of the cecum)
  2. Escherichia infection (bacterial infection by escherichia coli)
  3. Febrile neutropenia (fever with reduced white blood cells)
  4. Pneumonia
  5. Clostridial infection (infectious conditions by clostridium bacteria)
  6. Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
  7. Bacterial test positive
  8. Clostridium test positive

20-29:

  1. Abdominal pain
  2. Anaemia (lack of blood)
  3. Anorectal varices haemorrhage (dilation of collateral submucousal vessels due to backflow in the veins of the rectum with massive bleeding)
  4. Ascites (accumulation of fluid in the abdominal cavity)
  5. Asthenia (weakness)
  6. Blood lactic acid increased
  7. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  8. Coagulopathy (blood's ability to clot is impaired)
  9. Contusion (a type of hematoma of tissue in which capillaries)
  10. Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)

30-39:

  1. Brain abscess
  2. Injection site bruising
  3. Thrombosis (formation of a blood clot inside a blood vessel)

40-49:

n/a

50-59:

  1. Lethargy (tiredness)
  2. Oxygen saturation decreased
  3. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  4. Throat tightness
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  6. Anxiety
  7. Death
  8. Emotional distress
  9. Fear
  10. Injury

60+:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Stress
  4. Abdominal discomfort
  5. Abdominal distension
  6. Abdominal pain
  7. Ascites (accumulation of fluid in the abdominal cavity)
  8. Cardiac arrest
  9. Diarrhoea
  10. Hepatic function abnormal

What are the existing conditions these people have? *

  1. White Blood Cell Count Decreased: 3 people, 20.00%
  2. Tumor Lysis Syndrome: 3 people, 20.00%
  3. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 20.00%
  4. Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 3 people, 20.00%
  5. Chills (felling of cold): 3 people, 20.00%
  6. Fever: 3 people, 20.00%
  7. Gastritis (inflammation of stomach): 3 people, 20.00%
  8. Herpes Virus Infection: 3 people, 20.00%
  9. Hypocalcaemia (levels of calcium in blood serum are abnormally low): 3 people, 20.00%
  10. Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 3 people, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Demerol and Amicar?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Demerol and Amicar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Demerol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Amicar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Demerol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amicar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on meperidine hydrochloride and aminocaproic acid (the active ingredients of Demerol and Amicar, respectively), and Demerol and Amicar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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